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Progress in structure based drug design for G protein-coupled receptors.
Congreve M, Langmead CJ, Mason JS, Marshall FH. Congreve M, et al. Among authors: mason js. J Med Chem. 2011 Jul 14;54(13):4283-311. doi: 10.1021/jm200371q. Epub 2011 Jun 15. J Med Chem. 2011. PMID: 21615150 Free PMC article. Review. No abstract available.
Structure of Class B GPCRs: new horizons for drug discovery.
Bortolato A, Doré AS, Hollenstein K, Tehan BG, Mason JS, Marshall FH. Bortolato A, et al. Among authors: mason js. Br J Pharmacol. 2014 Jul;171(13):3132-45. doi: 10.1111/bph.12689. Br J Pharmacol. 2014. PMID: 24628305 Free PMC article. Review.
Intracellular allosteric antagonism of the CCR9 receptor.
Oswald C, Rappas M, Kean J, Doré AS, Errey JC, Bennett K, Deflorian F, Christopher JA, Jazayeri A, Mason JS, Congreve M, Cooke RM, Marshall FH. Oswald C, et al. Among authors: mason js. Nature. 2016 Dec 15;540(7633):462-465. doi: 10.1038/nature20606. Epub 2016 Dec 7. Nature. 2016. PMID: 27926729
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
Christopher JA, Orgován Z, Congreve M, Doré AS, Errey JC, Marshall FH, Mason JS, Okrasa K, Rucktooa P, Serrano-Vega MJ, Ferenczy GG, Keserű GM. Christopher JA, et al. Among authors: mason js. J Med Chem. 2019 Jan 10;62(1):207-222. doi: 10.1021/acs.jmedchem.7b01722. Epub 2018 Mar 1. J Med Chem. 2019. PMID: 29455526
Biophysical mapping of the adenosine A2A receptor.
Zhukov A, Andrews SP, Errey JC, Robertson N, Tehan B, Mason JS, Marshall FH, Weir M, Congreve M. Zhukov A, et al. Among authors: mason js. J Med Chem. 2011 Jul 14;54(13):4312-23. doi: 10.1021/jm2003798. Epub 2011 Jun 10. J Med Chem. 2011. PMID: 21661720 Free PMC article.
Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Jazayeri A, Rappas M, Brown AJH, Kean J, Errey JC, Robertson NJ, Fiez-Vandal C, Andrews SP, Congreve M, Bortolato A, Mason JS, Baig AH, Teobald I, Doré AS, Weir M, Cooke RM, Marshall FH. Jazayeri A, et al. Among authors: mason js. Nature. 2017 Jun 8;546(7657):254-258. doi: 10.1038/nature22800. Epub 2017 May 31. Nature. 2017. PMID: 28562585
72 results