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Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Bailus BJ, Scheeler SM, Simons J, Sanchez MA, Tshilenge KT, Creus-Muncunill J, Naphade S, Lopez-Ramirez A, Zhang N, Lakshika Madushani K, Moroz S, Loureiro A, Schreiber KH, Hausch F, Kennedy BK, Ehrlich ME, Ellerby LM. Bailus BJ, et al. Among authors: ehrlich me. Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24. Autophagy. 2021. PMID: 34024231 Free PMC article.
Chromatin plasticity and the pathogenesis of Huntington disease.
Ehrlich ME, Gandy S. Ehrlich ME, et al. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):16867-8. doi: 10.1073/pnas.1113321108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969556 Free PMC article. No abstract available.
185 results