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Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. Among authors: zhu h, zhu z. J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. J Cell Biol. 2015. PMID: 26323688 Free PMC article.
Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. Among authors: zhu h, zhu z. J Cell Biol. 2016 Mar 28;212(7):881-2. doi: 10.1083/jcb.20150304403082016c. Epub 2016 Mar 21. J Cell Biol. 2016. PMID: 27002169 Free PMC article. No abstract available.
TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.
Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J. Xu D, et al. Among authors: zhu h. Cell. 2018 Sep 6;174(6):1477-1491.e19. doi: 10.1016/j.cell.2018.07.041. Epub 2018 Aug 23. Cell. 2018. PMID: 30146158 Free PMC article.
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.
Xu D, Zhao H, Jin M, Zhu H, Shan B, Geng J, Dziedzic SA, Amin P, Mifflin L, Naito MG, Najafov A, Xing J, Yan L, Liu J, Qin Y, Hu X, Wang H, Zhang M, Manuel VJ, Tan L, He Z, Sun ZJ, Lee VMY, Wagner G, Yuan J. Xu D, et al. Among authors: zhu h. Nature. 2020 Nov;587(7832):133-138. doi: 10.1038/s41586-020-2757-z. Epub 2020 Sep 23. Nature. 2020. PMID: 32968279
Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response.
Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. Li W, et al. Among authors: zhu h. Cell Res. 2022 Jul;32(7):621-637. doi: 10.1038/s41422-022-00673-3. Epub 2022 Jun 3. Cell Res. 2022. PMID: 35661830 Free PMC article.
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Among authors: zhu h. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.
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