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The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
Thottakara T, Friedrich FW, Reischmann S, Braumann S, Schlossarek S, Krämer E, Juhr D, Schlüter H, van der Velden J, Münch J, Patten M, Eschenhagen T, Moog-Lutz C, Carrier L. Thottakara T, et al. Among authors: moog lutz c. J Mol Cell Cardiol. 2015 Oct;87:214-24. doi: 10.1016/j.yjmcc.2015.08.020. Epub 2015 Sep 3. J Mol Cell Cardiol. 2015. PMID: 26343497
Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells.
Spinner CA, Uttenweiler-Joseph S, Metais A, Stella A, Burlet-Schiltz O, Moog-Lutz C, Lamsoul I, Lutz PG. Spinner CA, et al. Among authors: moog lutz c. Sci Rep. 2015 Nov 5;5:16269. doi: 10.1038/srep16269. Sci Rep. 2015. PMID: 26537633 Free PMC article.
ASB2 targets filamins A and B to proteasomal degradation.
Heuzé ML, Lamsoul I, Baldassarre M, Lad Y, Lévêque S, Razinia Z, Moog-Lutz C, Calderwood DA, Lutz PG. Heuzé ML, et al. Blood. 2008 Dec 15;112(13):5130-40. doi: 10.1182/blood-2007-12-128744. Epub 2008 Sep 17. Blood. 2008. PMID: 18799729 Free PMC article.
Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?
Lamsoul I, Uttenweiler-Joseph S, Moog-Lutz C, Lutz PG. Lamsoul I, et al. Among authors: moog lutz c. Biochimie. 2016 Mar;122:339-47. doi: 10.1016/j.biochi.2015.08.003. Epub 2015 Aug 4. Biochimie. 2016. PMID: 26253693 Free article. Review.
ASB2α regulates migration of immature dendritic cells.
Lamsoul I, Métais A, Gouot E, Heuzé ML, Lennon-Duménil AM, Moog-Lutz C, Lutz PG. Lamsoul I, et al. Among authors: moog lutz c. Blood. 2013 Jul 25;122(4):533-41. doi: 10.1182/blood-2012-11-466649. Epub 2013 Apr 30. Blood. 2013. PMID: 23632887 Free article.
Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development.
Métais A, Lamsoul I, Melet A, Uttenweiler-Joseph S, Poincloux R, Stefanovic S, Valière A, Gonzalez de Peredo A, Stella A, Burlet-Schiltz O, Zaffran S, Lutz PG, Moog-Lutz C. Métais A, et al. Among authors: moog lutz c. Circ Res. 2018 Mar 16;122(6):e34-e48. doi: 10.1161/CIRCRESAHA.117.312015. Epub 2018 Jan 26. Circ Res. 2018. PMID: 29374072
33 results