Hamel E - Search Results

1

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.

Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, Schmidt-Supprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M. Ridder DA, et al. Among authors: hamel e. J Exp Med. 2015 Sep 21;212(10):1529-49. doi: 10.1084/jem.20150165. Epub 2015 Sep 7. J Exp Med. 2015. PMID: 26347470 Free PMC article.

2

Simvastatin restored vascular reactivity, endothelial function and reduced string vessel pathology in a mouse model of cerebrovascular disease.

Tong XK, Hamel E. Tong XK, et al. Among authors: hamel e. J Cereb Blood Flow Metab. 2015 Mar;35(3):512-20. doi: 10.1038/jcbfm.2014.226. Epub 2015 Jan 7. J Cereb Blood Flow Metab. 2015. PMID: 25564230 Free PMC article.

3

Transforming growth factor-beta 1 impairs endothelin-1-mediated contraction of brain vessels by inducing mitogen-activated protein (MAP) kinase phosphatase-1 and inhibiting p38 MAP kinase.

Tong XK, Hamel E. Tong XK, et al. Among authors: hamel e. Mol Pharmacol. 2007 Dec;72(6):1476-83. doi: 10.1124/mol.107.039602. Epub 2007 Sep 11. Mol Pharmacol. 2007. PMID: 17848599

4

Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease.

Zhang L, Papadopoulos P, Hamel E. Zhang L, et al. Among authors: hamel e. Br J Pharmacol. 2013 Oct;170(3):661-70. doi: 10.1111/bph.12315. Br J Pharmacol. 2013. PMID: 23889563 Free PMC article.

5

Losartan improves cerebrovascular function in a mouse model of Alzheimer's disease with combined overproduction of amyloid-β and transforming growth factor-β1.

Papadopoulos P, Tong XK, Imboden H, Hamel E. Papadopoulos P, et al. Among authors: hamel e. J Cereb Blood Flow Metab. 2017 Jun;37(6):1959-1970. doi: 10.1177/0271678X16658489. Epub 2016 Jan 1. J Cereb Blood Flow Metab. 2017. PMID: 27389178 Free PMC article.

6

High cholesterol triggers white matter alterations and cognitive deficits in a mouse model of cerebrovascular disease: benefits of simvastatin.

Tong XK, Trigiani LJ, Hamel E. Tong XK, et al. Among authors: hamel e. Cell Death Dis. 2019 Jan 28;10(2):89. doi: 10.1038/s41419-018-1199-0. Cell Death Dis. 2019. PMID: 30692517 Free PMC article.

7

Comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia.

Trigiani LJ, Royea J, Tong XK, Hamel E. Trigiani LJ, et al. Among authors: hamel e. FASEB J. 2019 Dec;33(12):13280-13293. doi: 10.1096/fj.201901002R. Epub 2019 Sep 26. FASEB J. 2019. PMID: 31557051 Free PMC article.

-Trigiani, L. J., Royea, J., Tong, X.-K., Hamel, E. Comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia....

-Trigiani, L. J., Royea, J., Tong, X.-K., Hamel, E. Comparative benefits of simvastatin and exercise in a mouse model of vascu …

8

Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease.

Papadopoulos P, Ongali B, Hamel E. Papadopoulos P, et al. Among authors: hamel e. Can J Physiol Pharmacol. 2010 Jun;88(6):652-60. doi: 10.1139/Y10-042. Can J Physiol Pharmacol. 2010. PMID: 20628431 Free article.

9

Cortical atrophy and hypoperfusion in a transgenic mouse model of Alzheimer's disease.

Hébert F, Grand'maison M, Ho MK, Lerch JP, Hamel E, Bedell BJ. Hébert F, et al. Among authors: hamel e. Neurobiol Aging. 2013 Jun;34(6):1644-52. doi: 10.1016/j.neurobiolaging.2012.11.022. Epub 2012 Dec 27. Neurobiol Aging. 2013. PMID: 23273599

10

Selective benefits of simvastatin in bitransgenic APPSwe,Ind/TGF-β1 mice.

Papadopoulos P, Tong XK, Hamel E. Papadopoulos P, et al. Among authors: hamel e. Neurobiol Aging. 2014 Jan;35(1):203-12. doi: 10.1016/j.neurobiolaging.2013.07.010. Epub 2013 Aug 15. Neurobiol Aging. 2014. PMID: 23954171

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