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Overexpression and knockout of miR-126 both promote leukemogenesis.
Li Z, Chen P, Su R, Li Y, Hu C, Wang Y, Arnovitz S, He M, Gurbuxani S, Zuo Z, Elkahloun AG, Li S, Weng H, Huang H, Neilly MB, Wang S, Olson EN, Larson RA, Le Beau MM, Zhang J, Jiang X, Wei M, Jin J, Liu PP, Chen J. Li Z, et al. Among authors: zhang j. Blood. 2015 Oct 22;126(17):2005-15. doi: 10.1182/blood-2015-04-639062. Epub 2015 Sep 11. Blood. 2015. PMID: 26361793 Free PMC article.
c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.
Guo Y, Niu C, Breslin P, Tang M, Zhang S, Wei W, Kini AR, Paner GP, Alkan S, Morris SW, Diaz M, Stiff PJ, Zhang J. Guo Y, et al. Among authors: zhang s, zhang j. Blood. 2009 Sep 3;114(10):2097-106. doi: 10.1182/blood-2009-01-197947. Epub 2009 Apr 16. Blood. 2009. PMID: 19372257 Free PMC article.
An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 axis controls myeloid development and transformation.
Fu CT, Zhu KY, Mi JQ, Liu YF, Murray ST, Fu YF, Ren CG, Dong ZW, Liu YJ, Dong M, Jin Y, Chen Y, Deng M, Zhang W, Chen B, Breslin P, Chen SJ, Chen Z, Becker MW, Zhu J, Zhang JW, Liu TX. Fu CT, et al. Among authors: zhang w, zhang jw. Blood. 2010 Jun 10;115(23):4715-24. doi: 10.1182/blood-2009-11-255778. Epub 2010 Apr 6. Blood. 2010. PMID: 20371743 Free PMC article.
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.
Li Z, Huang H, Chen P, He M, Li Y, Arnovitz S, Jiang X, He C, Hyjek E, Zhang J, Zhang Z, Elkahloun A, Cao D, Shen C, Wunderlich M, Wang Y, Neilly MB, Jin J, Wei M, Lu J, Valk PJM, Delwel R, Lowenberg B, Le Beau MM, Vardiman J, Mulloy JC, Zeleznik-Le NJ, Liu PP, Zhang J, Chen J. Li Z, et al. Among authors: zhang j, zhang z. Nat Commun. 2012 Feb 21;3:688. doi: 10.1038/ncomms1681. Nat Commun. 2012. PMID: 22353710 Free PMC article.
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Jiang X, Huang H, Li Z, Li Y, Wang X, Gurbuxani S, Chen P, He C, You D, Zhang S, Wang J, Arnovitz S, Elkahloun A, Price C, Hong GM, Ren H, Kunjamma RB, Neilly MB, Matthews JM, Xu M, Larson RA, Le Beau MM, Slany RK, Liu PP, Lu J, Zhang J, He C, Chen J. Jiang X, et al. Among authors: zhang s, zhang j. Cancer Cell. 2012 Oct 16;22(4):524-35. doi: 10.1016/j.ccr.2012.08.028. Cancer Cell. 2012. PMID: 23079661 Free PMC article.
Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.
Volk A, Li J, Xin J, You D, Zhang J, Liu X, Xiao Y, Breslin P, Li Z, Wei W, Schmidt R, Li X, Zhang Z, Kuo PC, Nand S, Zhang J, Chen J, Zhang J. Volk A, et al. Among authors: zhang j, zhang z. J Exp Med. 2014 Jun 2;211(6):1093-108. doi: 10.1084/jem.20130990. Epub 2014 May 19. J Exp Med. 2014. PMID: 24842373 Free PMC article.
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Jiang X, Hu C, Arnovitz S, Bugno J, Yu M, Zuo Z, Chen P, Huang H, Ulrich B, Gurbuxani S, Weng H, Strong J, Wang Y, Li Y, Salat J, Li S, Elkahloun AG, Yang Y, Neilly MB, Larson RA, Le Beau MM, Herold T, Bohlander SK, Liu PP, Zhang J, Li Z, He C, Jin J, Hong S, Chen J. Jiang X, et al. Among authors: zhang j. Nat Commun. 2016 Apr 26;7:11452. doi: 10.1038/ncomms11452. Nat Commun. 2016. PMID: 27116251 Free PMC article.
177,908 results
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