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The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2.
Chatterjee P, Canale V, King SJ, Shawki A, Lei H, Haddad M, Gries CM, McGovern DPB, Borneman J, McCole DF. Chatterjee P, et al. Among authors: shawki a. medRxiv [Preprint]. 2024 Sep 28:2024.09.26.24314341. doi: 10.1101/2024.09.26.24314341. medRxiv. 2024. PMID: 39399045 Free PMC article. Preprint.
Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice.
Deol P, Ruegger P, Logan GD, Shawki A, Li J, Mitchell JD, Yu J, Piamthai V, Radi SH, Hasnain S, Borkowski K, Newman JW, McCole DF, Nair MG, Hsiao A, Borneman J, Sladek FM. Deol P, et al. Among authors: shawki a. Gut Microbes. 2023 Jan-Dec;15(1):2229945. doi: 10.1080/19490976.2023.2229945. Gut Microbes. 2023. PMID: 37400966 Free PMC article.
PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice.
Canale V, Spalinger MR, Alvarez R, Sayoc-Becerra A, Sanati G, Manz S, Chatterjee P, Santos AN, Lei H, Jahng S, Chu T, Shawki A, Hanson E, Eckmann L, Ouellette AJ, McCole DF. Canale V, et al. Among authors: shawki a. Cell Mol Gastroenterol Hepatol. 2023;16(1):39-62. doi: 10.1016/j.jcmgh.2023.03.009. Epub 2023 Apr 7. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37030630 Free PMC article.
37 results