Schwartz EL - Search Results

1

RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors.

Cheng H, Zou Y, Ross JS, Wang K, Liu X, Halmos B, Ali SM, Liu H, Verma A, Montagna C, Chachoua A, Goel S, Schwartz EL, Zhu C, Shan J, Yu Y, Gritsman K, Yelensky R, Lipson D, Otto G, Hawryluk M, Stephens PJ, Miller VA, Piperdi B, Perez-Soler R. Cheng H, et al. Among authors: schwartz el. Cancer Discov. 2015 Dec;5(12):1262-70. doi: 10.1158/2159-8290.CD-14-0971. Epub 2015 Sep 14. Cancer Discov. 2015. PMID: 26370156 Free PMC article.

2

Antiangiogenic and antitumor activity of 6-(2-aminoethyl)amino-5-chlorouracil, a novel small-molecule inhibitor of thymidine phosphorylase, in combination with the vascular endothelial growth factor-trap.

Lu H, Klein RS, Schwartz EL. Lu H, et al. Among authors: schwartz el. Clin Cancer Res. 2009 Aug 15;15(16):5136-44. doi: 10.1158/1078-0432.CCR-08-3203. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671868 Free PMC article.

3

The autophagy inhibitor chloroquine overcomes the innate resistance of wild-type EGFR non-small-cell lung cancer cells to erlotinib.

Zou Y, Ling YH, Sironi J, Schwartz EL, Perez-Soler R, Piperdi B. Zou Y, et al. Among authors: schwartz el. J Thorac Oncol. 2013 Jun;8(6):693-702. doi: 10.1097/JTO.0b013e31828c7210. J Thorac Oncol. 2013. PMID: 23575415 Free PMC article.

4

Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells.

Nordstrøm LU, Sironi J, Aranda E, Maisonet J, Perez-Soler R, Wu P, Schwartz EL. Nordstrøm LU, et al. Among authors: schwartz el. ACS Med Chem Lett. 2015 Jan 8;6(2):134-9. doi: 10.1021/ml500348p. eCollection 2015 Feb 12. ACS Med Chem Lett. 2015. PMID: 25699157 Free PMC article.

5

Lysosome Membrane Permeabilization and Disruption of the Molecular Target of Rapamycin (mTOR)-Lysosome Interaction Are Associated with the Inhibition of Lung Cancer Cell Proliferation by a Chloroquinoline Analog.

Sironi J, Aranda E, Nordstrøm LU, Schwartz EL. Sironi J, et al. Among authors: schwartz el. Mol Pharmacol. 2019 Jan;95(1):127-138. doi: 10.1124/mol.118.113118. Epub 2018 Nov 8. Mol Pharmacol. 2019. PMID: 30409790 Free PMC article.

6

Targeted Inhibition of the E3 Ligase SCF^Skp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer.

Zhao H, Iqbal NJ, Sukrithan V, Nicholas C, Xue Y, Yu C, Locker J, Zou J, Schwartz EL, Zhu L. Zhao H, et al. Among authors: schwartz el. Cancer Res. 2020 Jun 1;80(11):2355-2367. doi: 10.1158/0008-5472.CAN-19-2400. Epub 2020 Apr 7. Cancer Res. 2020. PMID: 32265224 Free PMC article.

7

Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review.

Wadler S, Schwartz EL. Wadler S, et al. Among authors: schwartz el. Cancer Res. 1990 Jun 15;50(12):3473-86. Cancer Res. 1990. PMID: 1692761 Review.

8

5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression.

Schwartz EL, Baptiste N, Megati S, Wadler S, Otter BA. Schwartz EL, et al. Cancer Res. 1995 Aug 15;55(16):3543-50. Cancer Res. 1995. PMID: 7627962

9

Development of two radioimmunoassays to detect paclitaxel in sera and in cerebrospinal, ascitic, and pleural fluids.

O'Boyle KP, Wang Y, Schwartz EL, Regl DL, Einzig A, Dutcher JP, Wiernik PH, Horwitz SB. O'Boyle KP, et al. Among authors: schwartz el. Cancer. 1997 Mar 1;79(5):1022-30. doi: 10.1002/(sici)1097-0142(19970301)79:5<1022::aid-cncr20>3.0.co;2-2. Cancer. 1997. PMID: 9041166

10

All-trans retinoic acid and interferon-alpha-2a in patients with metastatic or recurrent carcinoma of the uterine cervix: clinical and pharmacokinetic studies. New York Gynecologic Oncology Group.

Wadler S, Schwartz EL, Haynes H, Rameau R, Quish A, Mandeli J, Gallagher R, Hallam S, Fields A, Goldberg G, McGill F, Jennings S, Wallach RC, Runowicz CD. Wadler S, et al. Among authors: schwartz el. Cancer. 1997 Apr 15;79(8):1574-80. doi: 10.1002/(sici)1097-0142(19970415)79:8<1574::aid-cncr20>3.0.co;2-u. Cancer. 1997. PMID: 9118041 Clinical Trial.

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