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The interferon type I signature is present in systemic sclerosis before overt fibrosis and might contribute to its pathogenesis through high BAFF gene expression and high collagen synthesis.
Brkic Z, van Bon L, Cossu M, van Helden-Meeuwsen CG, Vonk MC, Knaapen H, van den Berg W, Dalm VA, Van Daele PL, Severino A, Maria NI, Guillen S, Dik WA, Beretta L, Versnel MA, Radstake T. Brkic Z, et al. Among authors: dik wa. Ann Rheum Dis. 2016 Aug;75(8):1567-73. doi: 10.1136/annrheumdis-2015-207392. Epub 2015 Sep 14. Ann Rheum Dis. 2016. PMID: 26371289
198 results