Wu Y - Search Results

1

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.

Timmerman I, Heemskerk N, Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Unen J, Goedhart J, Gadella TW Jr, Yin T, Wu Y, Huveneers S, van Buul JD. Timmerman I, et al. Among authors: wu y. J Cell Sci. 2015 Sep 15;128(18):3514. doi: 10.1242/jcs.179424. J Cell Sci. 2015. PMID: 26374854 Free PMC article. No abstract available.

2

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.

Timmerman I, Heemskerk N, Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Unen J, Goedhart J, Gadella TW Jr, Yin T, Wu Y, Huveneers S, van Buul JD. Timmerman I, et al. Among authors: wu y. J Cell Sci. 2015 Aug 15;128(16):3041-54. doi: 10.1242/jcs.168674. Epub 2015 Jun 26. J Cell Sci. 2015. PMID: 26116572

3

F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling.

Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, Wu Y, Montanez E, Woodfin A, van Buul JD. Heemskerk N, et al. Among authors: wu y. Nat Commun. 2016 Jan 27;7:10493. doi: 10.1038/ncomms10493. Nat Commun. 2016. PMID: 26814335 Free PMC article.

4

The balance between Gα_i-Cdc42/Rac and Gα₁₂/₁₃-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate.

Reinhard NR, Mastop M, Yin T, Wu Y, Bosma EK, Gadella TWJ Jr, Goedhart J, Hordijk PL. Reinhard NR, et al. Among authors: wu y. Mol Biol Cell. 2017 Nov 7;28(23):3371-3382. doi: 10.1091/mbc.E17-03-0136. Epub 2017 Sep 27. Mol Biol Cell. 2017. PMID: 28954861 Free PMC article.

5

The C-terminus of the oncoprotein TGAT is necessary for plasma membrane association and efficient RhoA-mediated signaling.

van Unen J, Botman D, Yin T, Wu YI, Hink MA, Gadella TWJ Jr, Postma M, Goedhart J. van Unen J, et al. Among authors: wu yi. BMC Cell Biol. 2018 Jun 7;19(1):6. doi: 10.1186/s12860-018-0155-2. BMC Cell Biol. 2018. PMID: 29879899 Free PMC article.

6

Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization.

van Unen J, Reinhard NR, Yin T, Wu YI, Postma M, Gadella TW, Goedhart J. van Unen J, et al. Sci Rep. 2015 Oct 5;5:14693. doi: 10.1038/srep14693. Sci Rep. 2015. PMID: 26435194 Free PMC article.

7

Guiding lights: recent developments in optogenetic control of biochemical signals.

Yin T, Wu YI. Yin T, et al. Pflugers Arch. 2013 Mar;465(3):397-408. doi: 10.1007/s00424-013-1244-x. Epub 2013 Feb 16. Pflugers Arch. 2013. PMID: 23417571 Review.

8

Optogenetics: optical control of a photoactivatable Rac in living cells.

Yin T, Wu YI. Yin T, et al. Methods Mol Biol. 2015;1251:277-89. doi: 10.1007/978-1-4939-2080-8_15. Methods Mol Biol. 2015. PMID: 25391805

9

Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq.

van Unen J, Yin T, Wu YI, Mastop M, Gadella TW Jr, Goedhart J. van Unen J, et al. Sci Rep. 2016 Nov 11;6:36825. doi: 10.1038/srep36825. Sci Rep. 2016. PMID: 27833100 Free PMC article.

10

Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells.

Reinhard NR, van Helden SF, Anthony EC, Yin T, Wu YI, Goedhart J, Gadella TW, Hordijk PL. Reinhard NR, et al. Sci Rep. 2016 May 5;6:25502. doi: 10.1038/srep25502. Sci Rep. 2016. PMID: 27147504 Free PMC article.

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