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Page 1
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H; EUROSPAN Consortium; Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI; ENGAGE Consortium; Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani NJ, Schlessinger D, Uda M, Völker U, Waeber G, Waterworth D, Wang-Sattler R, Wright AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H; PROCARDIS Consortium; Doering A, Wichmann HE; KORA Study; Spector TD, Peltonen L, Völzke H, Nagaraja R, Vollenweider P, Caulfield M; WTCCC; Illig T, Gieger C. Kolz M, et al. Among authors: spector td. PLoS Genet. 2009 Jun;5(6):e1000504. doi: 10.1371/journal.pgen.1000504. Epub 2009 Jun 5. PLoS Genet. 2009. PMID: 19503597 Free PMC article.
Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis.
Valdes AM, Spector TD, Tamm A, Kisand K, Doherty SA, Dennison EM, Mangino M, Tamm A, Kerna I, Hart DJ, Wheeler M, Cooper C, Lories RJ, Arden NK, Doherty M. Valdes AM, et al. Among authors: spector td. Arthritis Rheum. 2010 Aug;62(8):2347-52. doi: 10.1002/art.27530. Arthritis Rheum. 2010. PMID: 20506137 Free article.
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.
Marzi C, Albrecht E, Hysi PG, Lagou V, Waldenberger M, Tönjes A, Prokopenko I, Heim K, Blackburn H, Ried JS, Kleber ME, Mangino M, Thorand B, Peters A, Hammond CJ, Grallert H, Boehm BO, Kovacs P, Geistlinger L, Prokisch H, Winkelmann BR, Spector TD, Wichmann HE, Stumvoll M, Soranzo N, März W, Koenig W, Illig T, Gieger C. Marzi C, et al. Among authors: spector td. PLoS Genet. 2010 Nov 18;6(11):e1001213. doi: 10.1371/journal.pgen.1001213. PLoS Genet. 2010. PMID: 21124955 Free PMC article.
A twin approach to unraveling epigenetics.
Bell JT, Spector TD. Bell JT, et al. Among authors: spector td. Trends Genet. 2011 Mar;27(3):116-25. doi: 10.1016/j.tig.2010.12.005. Epub 2011 Jan 21. Trends Genet. 2011. PMID: 21257220 Free PMC article. Review.
Genetic architecture of circulating lipid levels.
Demirkan A, Amin N, Isaacs A, Jarvelin MR, Whitfield JB, Wichmann HE, Kyvik KO, Rudan I, Gieger C, Hicks AA, Johansson Å, Hottenga JJ, Smith JJ, Wild SH, Pedersen NL, Willemsen G, Mangino M, Hayward C, Uitterlinden AG, Hofman A, Witteman J, Montgomery GW, Pietiläinen KH, Rantanen T, Kaprio J, Döring A, Pramstaller PP, Gyllensten U, de Geus EJ, Penninx BW, Wilson JF, Rivadeneria F, Magnusson PK, Boomsma DI, Spector T, Campbell H, Hoehne B, Martin NG, Oostra BA, McCarthy M, Peltonen-Palotie L, Aulchenko Y, Visscher PM, Ripatti S, Janssens AC, van Duijn CM; ENGAGE CONSORTIUM. Demirkan A, et al. Eur J Hum Genet. 2011 Jul;19(7):813-9. doi: 10.1038/ejhg.2011.21. Epub 2011 Mar 30. Eur J Hum Genet. 2011. PMID: 21448234 Free PMC article.
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.
Zhai G, Teumer A, Stolk L, Perry JR, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I; MuTHER Consortium; Nica A, Penninx BW, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Völzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H. Zhai G, et al. Among authors: spector td. PLoS Genet. 2011 Apr;7(4):e1002025. doi: 10.1371/journal.pgen.1002025. Epub 2011 Apr 14. PLoS Genet. 2011. PMID: 21533175 Free PMC article.
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.
Small KS, Hedman AK, Grundberg E, Nica AC, Thorleifsson G, Kong A, Thorsteindottir U, Shin SY, Richards HB; GIANT Consortium; MAGIC Investigators; DIAGRAM Consortium; Soranzo N, Ahmadi KR, Lindgren CM, Stefansson K, Dermitzakis ET, Deloukas P, Spector TD, McCarthy MI; MuTHER Consortium. Small KS, et al. Among authors: spector td. Nat Genet. 2011 Jun;43(6):561-4. doi: 10.1038/ng.833. Epub 2011 May 15. Nat Genet. 2011. PMID: 21572415 Free PMC article.
1,210 results