Li Y - Search Results

1

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. Min SW, et al. Among authors: li y. Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390242 Free PMC article.

2

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV Jr, Gan L. Minami SS, et al. Among authors: li y. Nat Med. 2014 Oct;20(10):1157-64. doi: 10.1038/nm.3672. Epub 2014 Sep 28. Nat Med. 2014. PMID: 25261995 Free PMC article.

3

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.

Tracy TE, Sohn PD, Minami SS, Wang C, Min SW, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R, Cong X, Schilling B, Ellerby LM, Huganir RL, Gan L. Tracy TE, et al. Among authors: li y. Neuron. 2016 Apr 20;90(2):245-60. doi: 10.1016/j.neuron.2016.03.005. Epub 2016 Mar 31. Neuron. 2016. PMID: 27041503 Free PMC article.

4

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.

Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L. Min SW, et al. Among authors: li y. J Neurosci. 2018 Apr 11;38(15):3680-3688. doi: 10.1523/JNEUROSCI.2369-17.2018. Epub 2018 Mar 14. J Neurosci. 2018. PMID: 29540553 Free PMC article.

5

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.

Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, Gan L. Sayed FA, et al. Among authors: li y. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10172-10177. doi: 10.1073/pnas.1811411115. Epub 2018 Sep 19. Proc Natl Acad Sci U S A. 2018. PMID: 30232263 Free PMC article.

6

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.

Zhan L, Krabbe G, Du F, Jones I, Reichert MC, Telpoukhovskaia M, Kodama L, Wang C, Cho SH, Sayed F, Li Y, Le D, Zhou Y, Shen Y, West B, Gan L. Zhan L, et al. Among authors: li y. PLoS Biol. 2019 Feb 8;17(2):e3000134. doi: 10.1371/journal.pbio.3000134. eCollection 2019 Feb. PLoS Biol. 2019. PMID: 30735499 Free PMC article.

7

Microglial microRNAs mediate sex-specific responses to tau pathology.

Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC, Clelland CD, Cheng Z, Yu G, Li Q, Kosik KS, Gan L. Kodama L, et al. Among authors: li y, li q. Nat Neurosci. 2020 Feb;23(2):167-171. doi: 10.1038/s41593-019-0560-7. Epub 2019 Dec 23. Nat Neurosci. 2020. PMID: 31873194 Free PMC article.

8

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.

Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. Chen X, et al. Among authors: li y. Mol Neurodegener. 2020 Jan 6;15(1):2. doi: 10.1186/s13024-019-0354-0. Mol Neurodegener. 2020. PMID: 31906970 Free PMC article.

9

Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.

Telpoukhovskaia MA, Liu K, Sayed FA, Etchegaray JI, Xie M, Zhan L, Li Y, Zhou Y, Le D, Bahr BA, Bogyo M, Ding S, Gan L. Telpoukhovskaia MA, et al. Among authors: li y. Sci Rep. 2020 Aug 13;10(1):13688. doi: 10.1038/s41598-020-70534-9. Sci Rep. 2020. PMID: 32792571 Free PMC article.

10

A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.

Zhan L, Fan L, Kodama L, Sohn PD, Wong MY, Mousa GA, Zhou Y, Li Y, Gan L. Zhan L, et al. Among authors: li y. Elife. 2020 Oct 15;9:e51796. doi: 10.7554/eLife.51796. Elife. 2020. PMID: 33054973 Free PMC article.

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