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105 results

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Page 1
Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice.
Sullivan JM, Badimon A, Schaefer U, Ayata P, Gray J, Chung CW, von Schimmelmann M, Zhang F, Garton N, Smithers N, Lewis H, Tarakhovsky A, Prinjha RK, Schaefer A. Sullivan JM, et al. Among authors: tarakhovsky a. J Exp Med. 2015 Oct 19;212(11):1771-81. doi: 10.1084/jem.20151271. Epub 2015 Sep 21. J Exp Med. 2015. PMID: 26392221 Free PMC article.
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response.
Fang TC, Schaefer U, Mecklenbrauker I, Stienen A, Dewell S, Chen MS, Rioja I, Parravicini V, Prinjha RK, Chandwani R, MacDonald MR, Lee K, Rice CM, Tarakhovsky A. Fang TC, et al. Among authors: tarakhovsky a. J Exp Med. 2012 Apr 9;209(4):661-9. doi: 10.1084/jem.20112343. Epub 2012 Mar 12. J Exp Med. 2012. PMID: 22412156 Free PMC article.
Chromatin targeting drugs in cancer and immunity.
Prinjha R, Tarakhovsky A. Prinjha R, et al. Among authors: tarakhovsky a. Genes Dev. 2013 Aug 15;27(16):1731-8. doi: 10.1101/gad.221895.113. Genes Dev. 2013. PMID: 23964091 Free PMC article. Review.
The "histone mimicry" by pathogens.
Schaefer U, Ho JS, Prinjha RK, Tarakhovsky A. Schaefer U, et al. Among authors: tarakhovsky a. Cold Spring Harb Symp Quant Biol. 2013;78:81-90. doi: 10.1101/sqb.2013.78.020339. Epub 2014 Apr 14. Cold Spring Harb Symp Quant Biol. 2013. PMID: 24733380 Free PMC article.
Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.
von Schimmelmann M, Feinberg PA, Sullivan JM, Ku SM, Badimon A, Duff MK, Wang Z, Lachmann A, Dewell S, Ma'ayan A, Han MH, Tarakhovsky A, Schaefer A. von Schimmelmann M, et al. Among authors: tarakhovsky a. Nat Neurosci. 2016 Oct;19(10):1321-30. doi: 10.1038/nn.4360. Epub 2016 Aug 15. Nat Neurosci. 2016. PMID: 27526204 Free PMC article.
Epigenetic drug discovery: breaking through the immune barrier.
Tough DF, Tak PP, Tarakhovsky A, Prinjha RK. Tough DF, et al. Among authors: tarakhovsky a. Nat Rev Drug Discov. 2016 Dec;15(12):835-853. doi: 10.1038/nrd.2016.185. Epub 2016 Oct 21. Nat Rev Drug Discov. 2016. PMID: 27765940 Review.
Epigenetic mechanisms of mental retardation.
Schaefer A, Tarakhovsky A, Greengard P. Schaefer A, et al. Among authors: tarakhovsky a. Prog Drug Res. 2011;67:125-46. doi: 10.1007/978-3-7643-8989-5_7. Prog Drug Res. 2011. PMID: 21141728 Review.
Suppression of the antiviral response by an influenza histone mimic.
Marazzi I, Ho JS, Kim J, Manicassamy B, Dewell S, Albrecht RA, Seibert CW, Schaefer U, Jeffrey KL, Prinjha RK, Lee K, García-Sastre A, Roeder RG, Tarakhovsky A. Marazzi I, et al. Among authors: tarakhovsky a. Nature. 2012 Mar 14;483(7390):428-33. doi: 10.1038/nature10892. Nature. 2012. PMID: 22419161 Free PMC article.
105 results