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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Deprez-Poulain R, Hennuyer N, Bosc D, Liang WG, Enée E, Marechal X, Charton J, Totobenazara J, Berte G, Jahklal J, Verdelet T, Dumont J, Dassonneville S, Woitrain E, Gauriot M, Paquet C, Duplan I, Hermant P, Cantrelle FX, Sevin E, Culot M, Landry V, Herledan A, Piveteau C, Lippens G, Leroux F, Tang WJ, van Endert P, Staels B, Deprez B. Deprez-Poulain R, et al. Among authors: van endert p. Nat Commun. 2015 Sep 23;6:8250. doi: 10.1038/ncomms9250. Nat Commun. 2015. PMID: 26394692 Free PMC article.
ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.
Énée É, Kratzer R, Arnoux JB, Barilleau E, Hamel Y, Marchi C, Beltrand J, Michaud B, Chatenoud L, Robert JJ, van Endert P. Énée É, et al. Among authors: van endert p. Diabetes. 2012 Jul;61(7):1779-84. doi: 10.2337/db12-0071. Epub 2012 May 14. Diabetes. 2012. PMID: 22586580 Free PMC article.
Production of an antigenic peptide by insulin-degrading enzyme.
Parmentier N, Stroobant V, Colau D, de Diesbach P, Morel S, Chapiro J, van Endert P, Van den Eynde BJ. Parmentier N, et al. Among authors: van den eynde bj, van endert p. Nat Immunol. 2010 May;11(5):449-54. doi: 10.1038/ni.1862. Epub 2010 Apr 4. Nat Immunol. 2010. PMID: 20364150
Multiple functions of insulin-degrading enzyme: a metabolic crosslight?
Tundo GR, Sbardella D, Ciaccio C, Grasso G, Gioia M, Coletta A, Polticelli F, Di Pierro D, Milardi D, Van Endert P, Marini S, Coletta M. Tundo GR, et al. Among authors: van endert p. Crit Rev Biochem Mol Biol. 2017 Oct;52(5):554-582. doi: 10.1080/10409238.2017.1337707. Epub 2017 Jun 21. Crit Rev Biochem Mol Biol. 2017. PMID: 28635330 Review.
185 results