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Page 1
Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease.
McRae BL, Levin AD, Wildenberg ME, Koelink PJ, Bousquet P, Mikaelian I, Sterman AS, Bryant S, D'Haens G, Kamath R, Salfeld J, van den Brink GR. McRae BL, et al. Among authors: koelink pj. J Crohns Colitis. 2016 Jan;10(1):69-76. doi: 10.1093/ecco-jcc/jjv179. Epub 2015 Oct 1. J Crohns Colitis. 2016. PMID: 26429698
Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages.
Levin AD, Koelink PJ, Bloemendaal FM, Vos AC, D'Haens GR, van den Brink GR, Wildenberg ME. Levin AD, et al. Among authors: koelink pj. J Crohns Colitis. 2016 Mar;10(3):323-9. doi: 10.1093/ecco-jcc/jjv174. Epub 2015 Sep 27. J Crohns Colitis. 2016. PMID: 26417049 Free PMC article.
The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines.
Wildenberg ME, Koelink PJ, Diederen K, Te Velde AA, Wolfkamp SC, Nuij VJ, Peppelenbosch MP, Nobis M, Sansom OJ, Anderson KI, van der Woude CJ, D'Haens GR, van den Brink GR. Wildenberg ME, et al. Among authors: koelink pj. Mucosal Immunol. 2017 Mar;10(2):352-360. doi: 10.1038/mi.2016.65. Epub 2016 Jul 20. Mucosal Immunol. 2017. PMID: 27435106 Free article.
Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis.
Bloemendaal FM, Levin AD, Wildenberg ME, Koelink PJ, McRae BL, Salfeld J, Lum J, van der Neut Kolfschoten M, Claassens JW, Visser R, Bentlage A, D'Haens GRAM, Verbeek JS, Vidarsson G, van den Brink GR. Bloemendaal FM, et al. Among authors: koelink pj. Gastroenterology. 2017 Nov;153(5):1351-1362.e4. doi: 10.1053/j.gastro.2017.07.021. Epub 2017 Jul 27. Gastroenterology. 2017. PMID: 28756234
Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model.
Wildenberg ME, Levin AD, Ceroni A, Guo Z, Koelink PJ, Hakvoort TBM, Westera L, Bloemendaal FM, Brandse JF, Simmons A, D'Haens GR, Ebner D, van den Brink GR. Wildenberg ME, et al. Among authors: koelink pj. J Crohns Colitis. 2017 Dec 4;11(12):1480-1490. doi: 10.1093/ecco-jcc/jjx104. J Crohns Colitis. 2017. PMID: 28961920 Free PMC article.
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response.
Westendorp BF, Büller NVJA, Karpus ON, van Dop WA, Koster J, Versteeg R, Koelink PJ, Snel CY, Meisner S, Roelofs JJTH, Uhmann A, Ver Loren van Themaat E, Heijmans J, Hahn H, Muncan V, Wildenberg ME, van den Brink GR. Westendorp BF, et al. Among authors: koelink pj. Cell Mol Gastroenterol Hepatol. 2017 Sep 5;5(1):67-82.e1. doi: 10.1016/j.jcmgh.2017.08.004. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29276753 Free PMC article.
Development of Reliable, Valid and Responsive Scoring Systems for Endoscopy and Histology in Animal Models for Inflammatory Bowel Disease.
Koelink PJ, Wildenberg ME, Stitt LW, Feagan BG, Koldijk M, van 't Wout AB, Atreya R, Vieth M, Brandse JF, Duijst S, Te Velde AA, D'Haens GRAM, Levesque BG, van den Brink GR. Koelink PJ, et al. J Crohns Colitis. 2018 Jun 28;12(7):794-803. doi: 10.1093/ecco-jcc/jjy035. J Crohns Colitis. 2018. PMID: 29608662 Free PMC article.
TNF-anti-TNF Immune Complexes Inhibit IL-12/IL-23 Secretion by Inflammatory Macrophages via an Fc-dependent Mechanism.
Bloemendaal FM, Koelink PJ, van Schie KA, Rispens T, Peters CP, Buskens CJ, van der Bilt JD, Bemelman WA, Korf H, Sabino JG, Ponsioen CY, Te Velde AA, D'Haens GRAM, Vermeire S, van den Brink GR, Wildenberg ME. Bloemendaal FM, et al. Among authors: koelink pj. J Crohns Colitis. 2018 Aug 29;12(9):1122-1130. doi: 10.1093/ecco-jcc/jjy075. J Crohns Colitis. 2018. PMID: 29860435
Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling.
Koelink PJ, Bloemendaal FM, Li B, Westera L, Vogels EWM, van Roest M, Gloudemans AK, van 't Wout AB, Korf H, Vermeire S, Te Velde AA, Ponsioen CY, D'Haens GR, Verbeek JS, Geiger TL, Wildenberg ME, van den Brink GR. Koelink PJ, et al. Gut. 2020 Jun;69(6):1053-1063. doi: 10.1136/gutjnl-2019-318264. Epub 2019 Sep 10. Gut. 2020. PMID: 31506328 Free PMC article.
49 results