Hempel JE - Search Results

1

Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Feaster TK, Cadar AG, Wang L, Williams CH, Chun YW, Hempel JE, Bloodworth N, Merryman WD, Lim CC, Wu JC, Knollmann BC, Hong CC. Feaster TK, et al. Among authors: hempel je. Circ Res. 2015 Dec 4;117(12):995-1000. doi: 10.1161/CIRCRESAHA.115.307580. Epub 2015 Oct 1. Circ Res. 2015. PMID: 26429802 Free PMC article.

2

Practical strategies for small-molecule probe development in chemical biology.

Hempel JE, Hong CC. Hempel JE, et al. Methods Mol Biol. 2015;1263:209-23. doi: 10.1007/978-1-4939-2269-7_17. Methods Mol Biol. 2015. PMID: 25618348

3

Development of thieno- and benzopyrimidinone inhibitors of the Hedgehog signaling pathway reveals PDE4-dependent and PDE4-independent mechanisms of action.

Hempel JE, Cadar AG, Hong CC. Hempel JE, et al. Bioorg Med Chem Lett. 2016 Apr 15;26(8):1947-53. doi: 10.1016/j.bmcl.2016.03.013. Epub 2016 Mar 7. Bioorg Med Chem Lett. 2016. PMID: 26976215 Free PMC article.

4

An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition.

Williams CH, Hempel JE, Hao J, Frist AY, Williams MM, Fleming JT, Sulikowski GA, Cooper MK, Chiang C, Hong CC. Williams CH, et al. Among authors: hempel je. Cell Rep. 2015 Apr 7;11(1):43-50. doi: 10.1016/j.celrep.2015.03.001. Epub 2015 Mar 26. Cell Rep. 2015. PMID: 25818300 Free PMC article.

5

Preface. Chemical biology.

Hempel JE, Williams CH, Hong CC. Hempel JE, et al. Methods Mol Biol. 2015;1263:v. Methods Mol Biol. 2015. PMID: 25774396 No abstract available.

6

Synthetic studies directed toward the AB decalin common to HMP-Y1 and hibarimicinone.

Hempel JE, Engers DW, Sulikowski GA. Hempel JE, et al. Tetrahedron Lett. 2014 Mar 26;55(13):2157-2159. doi: 10.1016/j.tetlet.2014.02.069. Epub 2014 Feb 26. Tetrahedron Lett. 2014. PMID: 32855575 Free PMC article.

7

Assignment and stereocontrol of hibarimicin atropoisomers.

Romaine IM, Hempel JE, Shanmugam G, Hori H, Igarashi Y, Polavarapu PL, Sulikowski GA. Romaine IM, et al. Among authors: hempel je. Org Lett. 2011 Sep 2;13(17):4538-41. doi: 10.1021/ol2017005. Epub 2011 Aug 3. Org Lett. 2011. PMID: 21812391 Free PMC article.

8

The application of vinylogous iminium salt derivatives to efficient formal syntheses of the marine akaloids lamellarin G trimethyl ether and ningalin B.

Gupton JT, Giglio BC, Eaton JE, Rieck EA, Smith KL, Keough MJ, Barelli PJ, Firich LT, Hempel JE, Smith TM, Kanters RP. Gupton JT, et al. Among authors: hempel je. Tetrahedron. 2009 May 30;65(22):4283-4292. doi: 10.1016/j.tet.2009.03.085. Tetrahedron. 2009. PMID: 20161334 Free PMC article.

9

The Application of Vinylogous Iminium Salt Derivatives and Microwave Accelerated Vilsmeier-Haack Reactions to Efficient Relay Syntheses of the Polycitone and Storniamide Natural Products.

Gupton JT, Banner EJ, Sartin MD, Coppock MB, Hempel JE, Kharlamova A, Fisher DC, Giglio BC, Smith KL, Keough MJ, Smith TM, Kanters RP, Dominey RN, Sikorski JA. Gupton JT, et al. Among authors: hempel je. Tetrahedron. 2008;64(22):5246-5253. doi: 10.1016/j.tet.2008.03.038. Tetrahedron. 2008. PMID: 18709182 Free PMC article.

10

Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole.

Mooberry SL, Weiderhold KN, Dakshanamurthy S, Hamel E, Banner EJ, Kharlamova A, Hempel J, Gupton JT, Brown ML. Mooberry SL, et al. Mol Pharmacol. 2007 Jul;72(1):132-40. doi: 10.1124/mol.107.034876. Epub 2007 Apr 24. Mol Pharmacol. 2007. PMID: 17456786

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