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Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration.
Zhao L, Spassieva S, Gable K, Gupta SD, Shi LY, Wang J, Bielawski J, Hicks WL, Krebs MP, Naggert J, Hannun YA, Dunn TM, Nishina PM. Zhao L, et al. Among authors: hannun ya. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):12962-7. doi: 10.1073/pnas.1516733112. Epub 2015 Oct 5. Proc Natl Acad Sci U S A. 2015. PMID: 26438849 Free PMC article.
Golgi fragmentation is associated with ceramide-induced cellular effects.
Hu W, Xu R, Zhang G, Jin J, Szulc ZM, Bielawski J, Hannun YA, Obeid LM, Mao C. Hu W, et al. Among authors: hannun ya. Mol Biol Cell. 2005 Mar;16(3):1555-67. doi: 10.1091/mbc.e04-07-0594. Epub 2005 Jan 12. Mol Biol Cell. 2005. PMID: 15647381 Free PMC article.
583 results