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Splenic Macrophage Subsets and Their Function during Blood-Borne Infections.
Borges da Silva H, Fonseca R, Pereira RM, Cassado Ados A, Álvarez JM, D'Império Lima MR. Borges da Silva H, et al. Among authors: fonseca r. Front Immunol. 2015 Sep 22;6:480. doi: 10.3389/fimmu.2015.00480. eCollection 2015. Front Immunol. 2015. PMID: 26441984 Free PMC article. Review.
In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria.
Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE. Borges da Silva H, et al. Among authors: fonseca r. PLoS Pathog. 2015 Feb 6;11(2):e1004598. doi: 10.1371/journal.ppat.1004598. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25658925 Free PMC article.
Chagas disease: still many unsolved issues.
Álvarez JM, Fonseca R, Borges da Silva H, Marinho CR, Bortoluci KR, Sardinha LR, Epiphanio S, D'Império Lima MR. Álvarez JM, et al. Among authors: fonseca r. Mediators Inflamm. 2014;2014:912965. doi: 10.1155/2014/912965. Epub 2014 Jun 29. Mediators Inflamm. 2014. PMID: 25104883 Free PMC article. Review.
MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control.
Santana DY, Salgado RM, Fevereiro M, Silva do Nascimento R, Fonseca R, Saraiva Câmara NO, Epiphanio S, Marinho CRF, Barreto-Chaves ML, D' Império-Lima MR, Álvarez JM. Santana DY, et al. Among authors: fonseca r. PLoS Negl Trop Dis. 2018 Aug 1;12(8):e0006617. doi: 10.1371/journal.pntd.0006617. eCollection 2018 Aug. PLoS Negl Trop Dis. 2018. PMID: 30067739 Free PMC article.
Developmental plasticity allows outside-in immune responses by resident memory T cells.
Fonseca R, Beura LK, Quarnstrom CF, Ghoneim HE, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D. Fonseca R, et al. Nat Immunol. 2020 Apr;21(4):412-421. doi: 10.1038/s41590-020-0607-7. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066954 Free PMC article.
The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.
Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC. Borges da Silva H, et al. Among authors: fonseca r. Nature. 2018 Jul;559(7713):264-268. doi: 10.1038/s41586-018-0282-0. Epub 2018 Jul 4. Nature. 2018. PMID: 29973721 Free PMC article.
Runx3 drives a CD8+ T cell tissue residency program that is absent in CD4+ T cells.
Fonseca R, Burn TN, Gandolfo LC, Devi S, Park SL, Obers A, Evrard M, Christo SN, Buquicchio FA, Lareau CA, McDonald KM, Sandford SK, Zamudio NM, Zanluqui NG, Zaid A, Speed TP, Satpathy AT, Mueller SN, Carbone FR, Mackay LK. Fonseca R, et al. Nat Immunol. 2022 Aug;23(8):1236-1245. doi: 10.1038/s41590-022-01273-4. Epub 2022 Jul 26. Nat Immunol. 2022. PMID: 35882933
1,493 results