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Bone stroma-derived cells change coregulators recruitment to androgen receptor and decrease cell proliferation in androgen-sensitive and castration-resistant prostate cancer cells.
Villagran MA, Gutierrez-Castro FA, Pantoja DF, Alarcon JC, Fariña MA, Amigo RF, Muñoz-Godoy NA, Pinilla MG, Peña EA, Gonzalez-Chavarria I, Toledo JR, Rivas CI, Vera JC, McNerney EM, Onate SA. Villagran MA, et al. Among authors: vera jc. Biochem Biophys Res Commun. 2015 Nov 27;467(4):1039-45. doi: 10.1016/j.bbrc.2015.10.009. Epub 2015 Oct 20. Biochem Biophys Res Commun. 2015. PMID: 26494300
Lectin-like oxidized LDL receptor-1 is an enhancer of tumor angiogenesis in human prostate cancer cells.
González-Chavarría I, Cerro RP, Parra NP, Sandoval FA, Zuñiga FA, Omazábal VA, Lamperti LI, Jiménez SP, Fernandez EA, Gutiérrez NA, Rodriguez FS, Onate SA, Sánchez O, Vera JC, Toledo JR. González-Chavarría I, et al. Among authors: vera jc. PLoS One. 2014 Aug 29;9(8):e106219. doi: 10.1371/journal.pone.0106219. eCollection 2014. PLoS One. 2014. PMID: 25170920 Free PMC article.
Sustained blockade of ascorbic acid transport associated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels after partial hepatectomy.
Maldonado M, Inostroza E, Peña E, Moncada N, Mardones L, Medina JL, Muñoz A, Gatica M, Villagrán M, Escobar E, Mendoza P, Roa FJ, González M, Guzmán P, Gutiérrez-Castro FA, Sweet K, Muñoz-Montesino C, Vera JC, Rivas CI. Maldonado M, et al. Among authors: vera jc. Free Radic Biol Med. 2017 Jul;108:655-667. doi: 10.1016/j.freeradbiomed.2017.04.006. Epub 2017 Apr 15. Free Radic Biol Med. 2017. PMID: 28419867
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.
Peña E, Roa FJ, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI. Peña E, et al. Among authors: vera jc. Free Radic Biol Med. 2019 May 1;135:283-292. doi: 10.1016/j.freeradbiomed.2019.03.015. Epub 2019 Mar 19. Free Radic Biol Med. 2019. PMID: 30902760
Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2. Activation by sodium and absolute dependence on bivalent cations.
Godoy A, Ormazabal V, Moraga-Cid G, Zúñiga FA, Sotomayor P, Barra V, Vasquez O, Montecinos V, Mardones L, Guzmán C, Villagrán M, Aguayo LG, Oñate SA, Reyes AM, Cárcamo JG, Rivas CI, Vera JC. Godoy A, et al. Among authors: vera jc. J Biol Chem. 2007 Jan 5;282(1):615-24. doi: 10.1074/jbc.M608300200. Epub 2006 Sep 29. J Biol Chem. 2007. PMID: 17012227 Free article.
Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione.
Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, van Zundert B, Bono MR, Oñate SA, Bustamante M, Cárcamo JG, Rivas CI, Vera JC. Montecinos V, et al. Among authors: vera jc. J Biol Chem. 2007 May 25;282(21):15506-15. doi: 10.1074/jbc.M608361200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403685 Free article.
Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2.
Muñoz-Montesino C, Roa FJ, Peña E, González M, Sotomayor K, Inostroza E, Muñoz CA, González I, Maldonado M, Soliz C, Reyes AM, Vera JC, Rivas CI. Muñoz-Montesino C, et al. Among authors: vera jc. Free Radic Biol Med. 2014 May;70:241-54. doi: 10.1016/j.freeradbiomed.2014.02.021. Epub 2014 Mar 2. Free Radic Biol Med. 2014. PMID: 24594434
138 results