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Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.
Van Liefferinge J, Bentea E, Demuyser T, Albertini G, Follin-Arbelet V, Holmseth S, Merckx E, Sato H, Aerts JL, Smolders I, Arckens L, Danbolt NC, Massie A. Van Liefferinge J, et al. Among authors: sato h. J Comp Neurol. 2016 Apr 1;524(5):1015-32. doi: 10.1002/cne.23889. Epub 2015 Oct 23. J Comp Neurol. 2016. PMID: 26494316
Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.
Bentea E, Demuyser T, Van Liefferinge J, Albertini G, Deneyer L, Nys J, Merckx E, Michotte Y, Sato H, Arckens L, Massie A, Smolders I. Bentea E, et al. Among authors: sato h. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jun 3;59:49-58. doi: 10.1016/j.pnpbp.2015.01.010. Epub 2015 Jan 23. Prog Neuropsychopharmacol Biol Psychiatry. 2015. PMID: 25619129 Free article.
Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
Merckx E, Albertini G, Paterka M, Jensen C, Albrecht P, Dietrich M, Van Liefferinge J, Bentea E, Verbruggen L, Demuyser T, Deneyer L, Lewerenz J, van Loo G, De Keyser J, Sato H, Maher P, Methner A, Massie A. Merckx E, et al. Among authors: sato h. J Neuroinflammation. 2017 Jan 13;14(1):9. doi: 10.1186/s12974-016-0787-0. J Neuroinflammation. 2017. PMID: 28086920 Free PMC article.
Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.
Demuyser T, Deneyer L, Bentea E, Albertini G, Femenia T, Walrave L, Sato H, Danbolt NC, De Bundel D, Michotte A, Lindskog M, Massie A, Smolders I. Demuyser T, et al. Among authors: sato h. World J Biol Psychiatry. 2019 Jun;20(5):381-392. doi: 10.1080/15622975.2017.1371332. Epub 2017 Sep 27. World J Biol Psychiatry. 2019. PMID: 28882088
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