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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Sanborn AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D, Cutkosky A, Li J, Geeting KP, Gnirke A, Melnikov A, McKenna D, Stamenova EK, Lander ES, Aiden EL. Sanborn AL, et al. Among authors: aiden el. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6456-65. doi: 10.1073/pnas.1518552112. Epub 2015 Oct 23. Proc Natl Acad Sci U S A. 2015. PMID: 26499245 Free PMC article.
Cicer super-pangenome provides insights into species evolution and agronomic trait loci for crop improvement in chickpea.
Khan AW, Garg V, Sun S, Gupta S, Dudchenko O, Roorkiwal M, Chitikineni A, Bayer PE, Shi C, Upadhyaya HD, Bohra A, Bharadwaj C, Mir RR, Baruch K, Yang B, Coyne CJ, Bansal KC, Nguyen HT, Ronen G, Aiden EL, Veneklaas E, Siddique KHM, Liu X, Edwards D, Varshney RK. Khan AW, et al. Among authors: aiden el. Nat Genet. 2024 Jun;56(6):1225-1234. doi: 10.1038/s41588-024-01760-4. Epub 2024 May 23. Nat Genet. 2024. PMID: 38783120
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.
Darrow EM, Huntley MH, Dudchenko O, Stamenova EK, Durand NC, Sun Z, Huang SC, Sanborn AL, Machol I, Shamim M, Seberg AP, Lander ES, Chadwick BP, Aiden EL. Darrow EM, et al. Among authors: aiden el. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4504-12. doi: 10.1073/pnas.1609643113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432957 Free PMC article.
Transferable model for chromosome architecture.
Di Pierro M, Zhang B, Aiden EL, Wolynes PG, Onuchic JN. Di Pierro M, et al. Among authors: aiden el. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12168-12173. doi: 10.1073/pnas.1613607113. Epub 2016 Sep 29. Proc Natl Acad Sci U S A. 2016. PMID: 27688758 Free PMC article.
Genome Organization Drives Chromosome Fragility.
Canela A, Maman Y, Jung S, Wong N, Callen E, Day A, Kieffer-Kwon KR, Pekowska A, Zhang H, Rao SSP, Huang SC, Mckinnon PJ, Aplan PD, Pommier Y, Aiden EL, Casellas R, Nussenzweig A. Canela A, et al. Among authors: aiden el. Cell. 2017 Jul 27;170(3):507-521.e18. doi: 10.1016/j.cell.2017.06.034. Epub 2017 Jul 20. Cell. 2017. PMID: 28735753 Free PMC article.
85 results