Shakeri-Nejad K - Search Results

1

Effects of Therapeutic and Supratherapeutic Doses of Siponimod (BAF312) on Cardiac Repolarization in Healthy Subjects.

Shakeri-Nejad K, Aslanis V, Veldandi UK, Mooney L, Pezous N, Brendani B, Juan A, Allison M, Perry R, Legangneux E. Shakeri-Nejad K, et al. Clin Ther. 2015 Nov 1;37(11):2489-2505.e2. doi: 10.1016/j.clinthera.2015.09.006. Epub 2015 Oct 27. Clin Ther. 2015. PMID: 26519230 Clinical Trial.

2

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation.

Feuerbach D, Pezous N, Weiss M, Shakeri-Nejad K, Lingenhoehl K, Hoyer D, Hurth K, Bilbe G, Pryce CR, McAllister K, Chaperon F, Kucher K, Johns D, Blaettler T, Lopez Lopez C. Feuerbach D, et al. Br J Pharmacol. 2015 Mar;172(5):1292-304. doi: 10.1111/bph.13001. Epub 2015 Jan 12. Br J Pharmacol. 2015. PMID: 25363835 Free PMC article. Clinical Trial.

3

Cardiac Effects of Siponimod (BAF312) Re-initiation After Variable Periods of Drug Discontinuation in Healthy Subjects.

Legangneux E, Shakeri-Nejad K, Aslanis V, Sagkriotis A, Pezous N, Brendani B, Behrje R, Gutierrez M. Legangneux E, et al. Clin Ther. 2016 Mar;38(3):631-45.e1. doi: 10.1016/j.clinthera.2016.01.021. Epub 2016 Feb 23. Clin Ther. 2016. PMID: 26916566 Clinical Trial.

4

Pharmacokinetics, safety, and tolerability of siponimod (BAF312) in subjects with different levels of hepatic impairment: a single-dose, open-label, parallel-group study .

Shakeri-Nejad K, Aslanis V, Veldandi UK, Gardin A, Zaehringer A, Dodman A, Su Z, Legangneux E. Shakeri-Nejad K, et al. Int J Clin Pharmacol Ther. 2017 Jan;55(1):41-53. doi: 10.5414/CP202588. Int J Clin Pharmacol Ther. 2017. PMID: 27443658 Clinical Trial.

5

Pharmacokinetics, safety, and tolerability of siponimod (BAF312) in subjects with severe renal impairment: A single-dose, open-label, parallel-group study .

Gardin A, Dodman A, Kalluri S, Neelakantham S, Tan X, Legangneux E, Shakeri-Nejad K. Gardin A, et al. Among authors: shakeri nejad k. Int J Clin Pharmacol Ther. 2017 Jan;55(1):54-65. doi: 10.5414/CP202608. Int J Clin Pharmacol Ther. 2017. PMID: 27841151 Clinical Trial.

6

Impact of siponimod on vaccination response in a randomized, placebo-controlled study.

Ufer M, Shakeri-Nejad K, Gardin A, Su Z, Paule I, Marbury TC, Legangneux E. Ufer M, et al. Among authors: shakeri nejad k. Neurol Neuroimmunol Neuroinflamm. 2017 Sep 13;4(6):e398. doi: 10.1212/NXI.0000000000000398. eCollection 2017 Nov. Neurol Neuroimmunol Neuroinflamm. 2017. PMID: 28955715 Free PMC article.

7

Effect of Fluconazole Coadministration and CYP2C9 Genetic Polymorphism on Siponimod Pharmacokinetics in Healthy Subjects.

Gardin A, Ufer M, Legangneux E, Rossato G, Jin Y, Su Z, Pal P, Li W, Shakeri-Nejad K. Gardin A, et al. Among authors: shakeri nejad k. Clin Pharmacokinet. 2019 Mar;58(3):349-361. doi: 10.1007/s40262-018-0700-3. Clin Pharmacokinet. 2019. PMID: 30088221 Free PMC article. Clinical Trial.

8

Siponimod pharmacokinetics, safety, and tolerability in combination with rifampin, a CYP2C9/3A4 inducer, in healthy subjects.

Gardin A, Gray C, Neelakantham S, Huth F, Davidson AM, Dumitras S, Legangneux E, Shakeri-Nejad K. Gardin A, et al. Among authors: shakeri nejad k. Eur J Clin Pharmacol. 2018 Dec;74(12):1593-1604. doi: 10.1007/s00228-018-2533-2. Epub 2018 Aug 13. Eur J Clin Pharmacol. 2018. PMID: 30105453

9

Siponimod pharmacokinetics, safety, and tolerability in combination with the potent CYP3A4 inhibitor itraconazole in healthy subjects with different CYP2C9 genotypes.

Gardin A, Shakeri-Nejad K, Feller A, Huth F, Neelakantham S, Dumitras S. Gardin A, et al. Among authors: shakeri nejad k. Eur J Clin Pharmacol. 2019 Nov;75(11):1565-1574. doi: 10.1007/s00228-019-02729-7. Epub 2019 Aug 7. Eur J Clin Pharmacol. 2019. PMID: 31392364 Clinical Trial.

10

Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Intravenous Siponimod: A Randomized, Open-label Study in Healthy Subjects.

Shakeri-Nejad K, Gardin A, Gray C, Neelakantham S, Dumitras S, Legangneux E. Shakeri-Nejad K, et al. Clin Ther. 2020 Jan;42(1):175-195. doi: 10.1016/j.clinthera.2019.11.014. Epub 2020 Jan 8. Clin Ther. 2020. PMID: 31926605 Free article. Clinical Trial.

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