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A histamine-independent itch pathway is required for allergic ocular itch.
Huang CC, Kim YS, Olson WP, Li F, Guo C, Luo W, Huang AJW, Liu Q. Huang CC, et al. Among authors: liu q. J Allergy Clin Immunol. 2016 Apr;137(4):1267-1270.e6. doi: 10.1016/j.jaci.2015.08.047. Epub 2015 Oct 28. J Allergy Clin Immunol. 2016. PMID: 26521042 Free PMC article.
TRPC3 Is Dispensable for β-Alanine Triggered Acute Itch.
Dong P, Guo C, Huang S, Ma M, Liu Q, Luo W. Dong P, et al. Among authors: liu q. Sci Rep. 2017 Oct 24;7(1):13869. doi: 10.1038/s41598-017-12770-0. Sci Rep. 2017. PMID: 29066740 Free PMC article.
Anatomical and functional dichotomy of ocular itch and pain.
Huang CC, Yang W, Guo C, Jiang H, Li F, Xiao M, Davidson S, Yu G, Duan B, Huang T, Huang AJW, Liu Q. Huang CC, et al. Among authors: liu q. Nat Med. 2018 Aug;24(8):1268-1276. doi: 10.1038/s41591-018-0083-x. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988128 Free PMC article.
Enhanced itch elicited by capsaicin in a chronic itch model.
Yu G, Yang N, Li F, Chen M, Guo CJ, Wang C, Hu D, Yang Y, Zhu C, Wang Z, Shi H, Gegen T, Tang M, He Q, Liu Q, Tang Z. Yu G, et al. Among authors: liu q. Mol Pain. 2016 Apr 26;12:1744806916645349. doi: 10.1177/1744806916645349. Print 2016. Mol Pain. 2016. PMID: 27118771 Free PMC article.
A basophil-neuronal axis promotes itch.
Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Wang F, et al. Among authors: liu q. Cell. 2021 Jan 21;184(2):422-440.e17. doi: 10.1016/j.cell.2020.12.033. Epub 2021 Jan 14. Cell. 2021. PMID: 33450207 Free PMC article.
Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem.
Li F, Jiang H, Shen X, Yang W, Guo C, Wang Z, Xiao M, Cui L, Luo W, Kim BS, Chen Z, Huang AJW, Liu Q. Li F, et al. Among authors: liu q. Cell. 2021 Jul 8;184(14):3762-3773.e10. doi: 10.1016/j.cell.2021.05.017. Epub 2021 Jun 15. Cell. 2021. PMID: 34133943 Free PMC article.
IL-33 signaling in sensory neurons promotes dry skin itch.
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. Trier AM, et al. Among authors: liu q. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. J Allergy Clin Immunol. 2022. PMID: 34560104 Free PMC article.
Peripheral Mechanisms of Itch.
Guo CJ, Grabinski NS, Liu Q. Guo CJ, et al. Among authors: liu q. J Invest Dermatol. 2022 Jan;142(1):31-41. doi: 10.1016/j.jid.2021.10.024. Epub 2021 Nov 24. J Invest Dermatol. 2022. PMID: 34838258 Free PMC article. Review.
Glutamate in primary afferents is required for itch transmission.
Cui L, Guo J, Cranfill SL, Gautam M, Bhattarai J, Olson W, Beattie K, Challis RC, Wu Q, Song X, Raabe T, Gradinaru V, Ma M, Liu Q, Luo W. Cui L, et al. Among authors: liu q. Neuron. 2022 Mar 2;110(5):809-823.e5. doi: 10.1016/j.neuron.2021.12.007. Epub 2022 Jan 4. Neuron. 2022. PMID: 34986325 Free PMC article.
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