Sánchez-Moreno M - Search Results

1

Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative.

Olmo F, Gómez-Contreras F, Navarro P, Marín C, Yunta MJ, Cano C, Campayo L, Martín-Oliva D, Rosales MJ, Sánchez-Moreno M. Olmo F, et al. Eur J Med Chem. 2015 Dec 1;106:106-19. doi: 10.1016/j.ejmech.2015.10.034. Epub 2015 Oct 23. Eur J Med Chem. 2015. PMID: 26523668

2

1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi.

Rodríguez-Ciria M, Sanz AM, Yunta MJ, Gómez-Contreras F, Navarro P, Sánchez-Moreno M, Boutaleb-Charki S, Osuna A, Castiñeiras A, Pardo M, Cano C, Campayo L. Rodríguez-Ciria M, et al. Bioorg Med Chem. 2007 Mar 1;15(5):2081-91. doi: 10.1016/j.bmc.2006.12.033. Epub 2006 Dec 23. Bioorg Med Chem. 2007. PMID: 17222558

3

Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings.

Sanz AM, Gómez-Contreras F, Navarro P, Sánchez-Moreno M, Boutaleb-Charki S, Campuzano J, Pardo M, Osuna A, Cano C, Yunta MJ, Campayo L. Sanz AM, et al. J Med Chem. 2008 Mar 27;51(6):1962-6. doi: 10.1021/jm701179m. Epub 2008 Feb 23. J Med Chem. 2008. PMID: 18293910

4

In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi.

Maldonado CR, Marín C, Olmo F, Huertas O, Quirós M, Sánchez-Moreno M, Rosales MJ, Salas JM. Maldonado CR, et al. J Med Chem. 2010 Oct 14;53(19):6964-72. doi: 10.1021/jm100581z. J Med Chem. 2010. PMID: 20812723

5

In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.

Sánchez-Moreno M, Sanz AM, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macias I, Rosales MJ, Olmo F, Garcia-Aranda I, Campayo L, Cano C, Arrebola F, Yunta MJ. Sánchez-Moreno M, et al. J Med Chem. 2011 Feb 24;54(4):970-9. doi: 10.1021/jm101198k. Epub 2011 Jan 13. J Med Chem. 2011. PMID: 21229977

6

In vitro and in vivo trypanocidal activity of flavonoids from Delphinium staphisagria against Chagas disease.

Marín C, Ramírez-Macías I, López-Céspedes A, Olmo F, Villegas N, Díaz JG, Rosales MJ, Gutiérrez-Sánchez R, Sánchez-Moreno M. Marín C, et al. J Nat Prod. 2011 Apr 25;74(4):744-50. doi: 10.1021/np1008043. Epub 2011 Apr 5. J Nat Prod. 2011. PMID: 21466157

7

In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species.

Sánchez-Moreno M, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macías I, Olmo F, Sanz AM, Campayo L, Cano C, Yunta MJ. Sánchez-Moreno M, et al. J Antimicrob Chemother. 2012 Feb;67(2):387-97. doi: 10.1093/jac/dkr480. Epub 2011 Nov 29. J Antimicrob Chemother. 2012. PMID: 22127582

8

In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: their action on acute and chronic phases of Chagas disease.

Sánchez-Moreno M, Marín C, Navarro P, Lamarque L, García-España E, Miranda C, Huertas O, Olmo F, Gómez-Contreras F, Pitarch J, Arrebola F. Sánchez-Moreno M, et al. J Med Chem. 2012 May 10;55(9):4231-43. doi: 10.1021/jm2017144. Epub 2012 Apr 24. J Med Chem. 2012. PMID: 22443115

9

In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi.

Ramírez-Macías I, Marín C, Chahboun R, Messouri I, Olmo F, Rosales MJ, Gutierrez-Sánchez R, Alvarez-Manzaneda E, Sánchez-Moreno M. Ramírez-Macías I, et al. Am J Trop Med Hyg. 2012 Sep;87(3):481-8. doi: 10.4269/ajtmh.2012.11-0471. Epub 2012 Jul 16. Am J Trop Med Hyg. 2012. PMID: 22802442 Free PMC article.

10

Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection.

Sánchez-Moreno M, Gómez-Contreras F, Navarro P, Marín C, Olmo F, Yunta MJ, Sanz AM, Rosales MJ, Cano C, Campayo L. Sánchez-Moreno M, et al. J Med Chem. 2012 Nov 26;55(22):9900-13. doi: 10.1021/jm3011004. Epub 2012 Oct 22. J Med Chem. 2012. PMID: 23043291

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