Hesek D - Search Results

1

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence.

Rico-Lastres P, Díez-Martínez R, Iglesias-Bexiga M, Bustamante N, Aldridge C, Hesek D, Lee M, Mobashery S, Gray J, Vollmer W, García P, Menéndez M. Rico-Lastres P, et al. Among authors: hesek d. Sci Rep. 2015 Nov 5;5:16198. doi: 10.1038/srep16198. Sci Rep. 2015. PMID: 26537571 Free PMC article.

2

A mechanism-based inhibitor targeting the DD-transpeptidase activity of bacterial penicillin-binding proteins.

Lee M, Hesek D, Suvorov M, Lee W, Vakulenko S, Mobashery S. Lee M, et al. Among authors: hesek d. J Am Chem Soc. 2003 Dec 31;125(52):16322-6. doi: 10.1021/ja038445l. J Am Chem Soc. 2003. PMID: 14692773

3

Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria.

Hesek D, Suvorov M, Morio K, Lee M, Brown S, Vakulenko SB, Mobashery S. Hesek D, et al. J Org Chem. 2004 Feb 6;69(3):778-84. doi: 10.1021/jo035397e. J Org Chem. 2004. PMID: 14750804

4

Synthesis of a fragment of bacterial cell wall.

Hesek D, Lee M, Morio K, Mobashery S. Hesek D, et al. J Org Chem. 2004 Mar 19;69(6):2137-46. doi: 10.1021/jo035583k. J Org Chem. 2004. PMID: 15058963

5

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase.

Toth M, Osenkowski P, Hesek D, Brown S, Meroueh S, Sakr W, Mobashery S, Fridman R. Toth M, et al. Among authors: hesek d. Biochem J. 2005 Apr 15;387(Pt 2):497-506. doi: 10.1042/BJ20041324. Biochem J. 2005. PMID: 15560752 Free PMC article.

6

A practical synthesis of nitrocefin.

Lee M, Hesek D, Mobashery S. Lee M, et al. Among authors: hesek d. J Org Chem. 2005 Jan 7;70(1):367-9. doi: 10.1021/jo0487395. J Org Chem. 2005. PMID: 15624952

7

Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall.

Fuda C, Hesek D, Lee M, Morio K, Nowak T, Mobashery S. Fuda C, et al. Among authors: hesek d. J Am Chem Soc. 2005 Feb 23;127(7):2056-7. doi: 10.1021/ja0434376. J Am Chem Soc. 2005. PMID: 15713078

8

Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus.

Fuda C, Hesek D, Lee M, Heilmayer W, Novak R, Vakulenko SB, Mobashery S. Fuda C, et al. Among authors: hesek d. J Biol Chem. 2006 Apr 14;281(15):10035-41. doi: 10.1074/jbc.M508846200. Epub 2006 Feb 3. J Biol Chem. 2006. PMID: 16459335 Free article.

9

Three-dimensional structure of the bacterial cell wall peptidoglycan.

Meroueh SO, Bencze KZ, Hesek D, Lee M, Fisher JF, Stemmler TL, Mobashery S. Meroueh SO, et al. Among authors: hesek d. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4404-9. doi: 10.1073/pnas.0510182103. Epub 2006 Mar 9. Proc Natl Acad Sci U S A. 2006. PMID: 16537437 Free PMC article.

10

Side reaction of significance in preparation of peptide- or peptidomimetic-based hydroxamate enzyme inhibitors.

Hesek D, Noll BC, Mobashery S. Hesek D, et al. J Org Chem. 2006 Mar 31;71(7):2885-7. doi: 10.1021/jo052546f. J Org Chem. 2006. PMID: 16555848

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