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Page 1
Increased pretreatment serum IFN-β/α ratio predicts non-response to tumour necrosis factor α inhibition in rheumatoid arthritis.
Wampler Muskardin T, Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Kern M, Curtis JR, Danila MI, Cofield SS, Shadick N, Nigrovic PA, St Clair EW, Bingham CO 3rd, Furie R, Robinson W, Genovese M, Striebich CC, O'Dell JR, Thiele GM, Moreland LW, Levesque M, Bridges SL Jr, Gregersen PK, Niewold TB. Wampler Muskardin T, et al. Among authors: kern m. Ann Rheum Dis. 2016 Oct;75(10):1757-62. doi: 10.1136/annrheumdis-2015-208001. Epub 2015 Nov 6. Ann Rheum Dis. 2016. PMID: 26546586 Free PMC article.
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Herenius M, Weinblatt ME, Shadick NA, Worthington J, Batliwalla F, Kern M, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Seldin MF, Moreland LW, Behrens TW, Allaart CF, Criswell LA, Huizinga TW, Tak PP, Bridges SL Jr, Toes RE, Barton A, Klareskog L, Gregersen PK, Karlson EW, Plenge RM. Cui J, et al. Among authors: kern m. Arthritis Rheum. 2010 Jul;62(7):1849-61. doi: 10.1002/art.27457. Arthritis Rheum. 2010. PMID: 20309874 Free PMC article.
Modular analysis of peripheral blood gene expression in rheumatoid arthritis captures reproducible gene expression changes in tumor necrosis factor responders.
Oswald M, Curran ME, Lamberth SL, Townsend RM, Hamilton JD, Chernoff DN, Carulli J, Townsend MJ, Weinblatt ME, Kern M, Pond CM, Lee A, Gregersen PK. Oswald M, et al. Among authors: kern m. Arthritis Rheumatol. 2015 Feb;67(2):344-51. doi: 10.1002/art.38947. Arthritis Rheumatol. 2015. PMID: 25371395 Free PMC article.
Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.
Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, Dupuis J, Plenge RM, Coenen MJ, Behrens TW, Carulli JP, Gregersen PK. Liu C, et al. Among authors: kern m. Mol Med. 2008 Sep-Oct;14(9-10):575-81. doi: 10.2119/2008-00056.Liu. Mol Med. 2008. PMID: 18615156 Free PMC article.
Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.
Knevel R, Klein K, Somers K, Ospelt C, Houwing-Duistermaat JJ, van Nies JA, de Rooy DP, de Bock L, Kurreeman FA, Schonkeren J, Stoeken-Rijsbergen G, Helmer Q, van der Linden MP, Kern M, Manjarrez-Orduno N, Rodriguez-Rodriquez L, Stinissen P, Huizinga TW, Toes RE, Gay S, Gregersen PK, Somers V, van der Helm-van Mil AH. Knevel R, et al. Among authors: kern m. Ann Rheum Dis. 2014 Nov;73(11):2038-46. doi: 10.1136/annrheumdis-2013-204050. Epub 2013 Aug 16. Ann Rheum Dis. 2014. PMID: 23956247 Free PMC article.
Gene expression patterns in peripheral blood cells associated with radiographic severity in African Americans with early rheumatoid arthritis.
Reynolds RJ, Cui X, Vaughan LK, Redden DT, Causey Z, Perkins E, Shah T, Hughes LB; CLEAR Investigators; Damle A, Kern M, Gregersen PK, Johnson MR, Bridges SL Jr. Reynolds RJ, et al. Among authors: kern m. Rheumatol Int. 2013 Jan;33(1):129-37. doi: 10.1007/s00296-011-2355-3. Epub 2012 Jan 12. Rheumatol Int. 2013. PMID: 22238028 Free PMC article.
Peripheral blood gene expression profiling in rheumatoid arthritis.
Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK. Batliwalla FM, et al. Among authors: kern m. Genes Immun. 2005 Aug;6(5):388-97. doi: 10.1038/sj.gene.6364209. Genes Immun. 2005. PMID: 15973463
Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts.
Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, Wolfe F, Lum RF, Massarotti E, Weisman M, Bombardier C, Karlson EW, Criswell LA, Vlietinck R, Gregersen PK. Lee HS, et al. Among authors: kern m. Arthritis Rheum. 2007 Jun;56(6):1745-53. doi: 10.1002/art.22703. Arthritis Rheum. 2007. PMID: 17530703 Free article.
A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases.
Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK. Jawaheer D, et al. Among authors: kern m. Am J Hum Genet. 2001 Apr;68(4):927-36. doi: 10.1086/319518. Epub 2001 Mar 9. Am J Hum Genet. 2001. PMID: 11254450 Free PMC article.
1,865 results