Shadel GS - Search Results

1

Auditory Pathology in a Transgenic mtTFB1 Mouse Model of Mitochondrial Deafness.

McKay SE, Yan W, Nouws J, Thormann MJ, Raimundo N, Khan A, Santos-Sacchi J, Song L, Shadel GS. McKay SE, et al. Among authors: shadel gs. Am J Pathol. 2015 Dec;185(12):3132-40. doi: 10.1016/j.ajpath.2015.08.014. Epub 2015 Nov 6. Am J Pathol. 2015. PMID: 26552864 Free PMC article.

2

Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions.

Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W. Zhang H, et al. Am J Pathol. 2007 Mar;170(3):1108-20. doi: 10.2353/ajpath.2007.060960. Am J Pathol. 2007. PMID: 17322393 Free PMC article.

3

Expression and maintenance of mitochondrial DNA: new insights into human disease pathology.

Shadel GS. Shadel GS. Am J Pathol. 2008 Jun;172(6):1445-56. doi: 10.2353/ajpath.2008.071163. Epub 2008 May 5. Am J Pathol. 2008. PMID: 18458094 Free PMC article.

4

Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness.

Cotney J, McKay SE, Shadel GS. Cotney J, et al. Among authors: shadel gs. Hum Mol Genet. 2009 Jul 15;18(14):2670-82. doi: 10.1093/hmg/ddp208. Epub 2009 May 5. Hum Mol Genet. 2009. PMID: 19417006 Free PMC article.

5

A "radical" mitochondrial view of autophagy-related pathology.

Raimundo N, Shadel GS. Raimundo N, et al. Among authors: shadel gs. Aging (Albany NY). 2009 Apr 8;1(4):354-6. doi: 10.18632/aging.100037. Aging (Albany NY). 2009. PMID: 20157522 Free PMC article. No abstract available.

6

Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.

D'Souza AD, Parish IA, McKay SE, Kaech SM, Shadel GS. D'Souza AD, et al. Among authors: shadel gs. Am J Pathol. 2011 Jun;178(6):2740-51. doi: 10.1016/j.ajpath.2011.02.022. Am J Pathol. 2011. PMID: 21641396 Free PMC article.

7

Revisiting the TCA cycle: signaling to tumor formation.

Raimundo N, Baysal BE, Shadel GS. Raimundo N, et al. Among authors: shadel gs. Trends Mol Med. 2011 Nov;17(11):641-9. doi: 10.1016/j.molmed.2011.06.001. Epub 2011 Jul 20. Trends Mol Med. 2011. PMID: 21764377 Free PMC article. Review.

8

Genomic imprinting at a boundary element flanking the SDHD locus.

Baysal BE, McKay SE, Kim YJ, Zhang Z, Alila L, Willett-Brozick JE, Pacak K, Kim TH, Shadel GS. Baysal BE, et al. Among authors: shadel gs. Hum Mol Genet. 2011 Nov 15;20(22):4452-61. doi: 10.1093/hmg/ddr376. Epub 2011 Aug 23. Hum Mol Genet. 2011. PMID: 21862453 Free PMC article.

9

Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.

Woo DK, Green PD, Santos JH, D'Souza AD, Walther Z, Martin WD, Christian BE, Chandel NS, Shadel GS. Woo DK, et al. Among authors: shadel gs. Am J Pathol. 2012 Jan;180(1):24-31. doi: 10.1016/j.ajpath.2011.10.003. Epub 2011 Nov 3. Am J Pathol. 2012. PMID: 22056359 Free PMC article.

10

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness.

Raimundo N, Song L, Shutt TE, McKay SE, Cotney J, Guan MX, Gilliland TC, Hohuan D, Santos-Sacchi J, Shadel GS. Raimundo N, et al. Among authors: shadel gs. Cell. 2012 Feb 17;148(4):716-26. doi: 10.1016/j.cell.2011.12.027. Cell. 2012. PMID: 22341444 Free PMC article.

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