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Page 1
Natural and synthetic flavonoid modulation of TRPC5 channels.
Naylor J, Minard A, Gaunt HJ, Amer MS, Wilson LA, Migliore M, Cheung SY, Rubaiy HN, Blythe NM, Musialowski KE, Ludlow MJ, Evans WD, Green BL, Yang H, You Y, Li J, Fishwick CW, Muraki K, Beech DJ, Bon RS. Naylor J, et al. Among authors: cheung sy. Br J Pharmacol. 2016 Feb;173(3):562-74. doi: 10.1111/bph.13387. Epub 2016 Jan 13. Br J Pharmacol. 2016. PMID: 26565375 Free PMC article.
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
Rubaiy HN, Ludlow MJ, Henrot M, Gaunt HJ, Miteva K, Cheung SY, Tanahashi Y, Hamzah N, Musialowski KE, Blythe NM, Appleby HL, Bailey MA, McKeown L, Taylor R, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Muraki K, Beech DJ. Rubaiy HN, et al. Among authors: cheung sy. J Biol Chem. 2017 May 19;292(20):8158-8173. doi: 10.1074/jbc.M116.773556. Epub 2017 Mar 21. J Biol Chem. 2017. PMID: 28325835 Free PMC article.
TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.
Cheung SY, Henrot M, Al-Saad M, Baumann M, Muller H, Unger A, Rubaiy HN, Mathar I, Dinkel K, Nussbaumer P, Klebl B, Freichel M, Rode B, Trainor S, Clapcote SJ, Christmann M, Waldmann H, Abbas SK, Beech DJ, Vasudev NS. Cheung SY, et al. Oncotarget. 2018 Jul 3;9(51):29634-29643. doi: 10.18632/oncotarget.25659. eCollection 2018 Jul 3. Oncotarget. 2018. PMID: 30038709 Free PMC article.
An upregulation in the expression of vanilloid transient potential channels 2 enhances hypotonicity-induced cytosolic Ca²⁺ rise in human induced pluripotent stem cell model of Hutchinson-Gillford Progeria.
Lo CY, Tjong YW, Ho JC, Siu CW, Cheung SY, Tang NL, Yu S, Tse HF, Yao X. Lo CY, et al. Among authors: cheung sy. PLoS One. 2014 Jan 27;9(1):e87273. doi: 10.1371/journal.pone.0087273. eCollection 2014. PLoS One. 2014. PMID: 24475260 Free PMC article.
Model-Informed Drug Development (MIDD) for Antimicrobials.
Lin YW, Cheung SYA. Lin YW, et al. Among authors: cheung sya. Int J Antimicrob Agents. 2024 Dec;64(6):107392. doi: 10.1016/j.ijantimicag.2024.107392. Epub 2024 Nov 15. Int J Antimicrob Agents. 2024. PMID: 39549766 No abstract available.
Pediatric Rare Diseases Development in the Pharmaceutical Industry: An International Consortium for Innovation and Quality in Pharmaceutical Development, Clinical Pharmacology Leadership Group-Pediatrics Working Group, Rare Diseases Subteam Whitepaper Examining the Current Landscape and Recommendations for the Future.
Krishna R, Sebastien B, Corriol-Rohou S, Cheung SYA, Liu J, Suryawanshi S. Krishna R, et al. Among authors: cheung sya. Clin Pharmacol Ther. 2024 Dec;116(6):1433-1441. doi: 10.1002/cpt.3422. Epub 2024 Aug 15. Clin Pharmacol Ther. 2024. PMID: 39145605 Review.
Safety and pharmacokinetics of oral and long-acting injectable cabotegravir or long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study.
Gaur AH, Capparelli EV, Calabrese K, Baltrusaitis K, Marzinke MA, McCoig C, Van Solingen-Ristea RM, Mathiba SR, Adeyeye A, Moye JH, Heckman B, Lowenthal ED, Ward S, Milligan R, Samson P, Best BM, Harrington CM, Ford SL, Huang J, Crauwels H, Vandermeulen K, Agwu AL, Smith-Anderson C, Camacho-Gonzalez A, Ounchanum P, Kneebone JL, Townley E, Bolton Moore C; IMPAACT 2017 Collaborators; IMPAACT 2017 Team. Gaur AH, et al. Lancet HIV. 2024 Apr;11(4):e211-e221. doi: 10.1016/S2352-3018(23)00300-4. Lancet HIV. 2024. PMID: 38538160 Clinical Trial.
Pediatric oncology drug development and dosage optimization.
Cheung SYA, Hay JL, Lin YW, de Greef R, Bullock J. Cheung SYA, et al. Front Oncol. 2024 Jan 29;13:1235947. doi: 10.3389/fonc.2023.1235947. eCollection 2023. Front Oncol. 2024. PMID: 38348118 Free PMC article. Review.
119 results