Benkovic SJ - Search Results

1

Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase.

Stura EA, Johnson DL, Inglese J, Smith JM, Benkovic SJ, Wilson IA. Stura EA, et al. Among authors: benkovic sj. J Biol Chem. 1989 Jun 5;264(16):9703-6. J Biol Chem. 1989. PMID: 2656702 Free article.

2

Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.

Chen P, Schulze-Gahmen U, Stura EA, Inglese J, Johnson DL, Marolewski A, Benkovic SJ, Wilson IA. Chen P, et al. Among authors: benkovic sj. J Mol Biol. 1992 Sep 5;227(1):283-92. doi: 10.1016/0022-2836(92)90698-j. J Mol Biol. 1992. PMID: 1522592

3

Subcloning, characterization, and affinity labeling of Escherichia coli glycinamide ribonucleotide transformylase.

Inglese J, Johnson DL, Shiau A, Smith JM, Benkovic SJ. Inglese J, et al. Among authors: benkovic sj. Biochemistry. 1990 Feb 13;29(6):1436-43. doi: 10.1021/bi00458a014. Biochemistry. 1990. PMID: 2185839

4

Active-site mapping and site-specific mutagenesis of glycinamide ribonucleotide transformylase from Escherichia coli.

Inglese J, Smith JM, Benkovic SJ. Inglese J, et al. Among authors: benkovic sj. Biochemistry. 1990 Jul 17;29(28):6678-87. doi: 10.1021/bi00480a018. Biochemistry. 1990. PMID: 2204419

5

Direct demonstration of the active salvage of preformed purines by murine tumors.

Johnson DL, Mullin RJ, Duch DS, Benkovic SJ. Johnson DL, et al. Among authors: benkovic sj. Biochem Biophys Res Commun. 1990 Aug 16;170(3):1164-9. doi: 10.1016/0006-291x(90)90515-o. Biochem Biophys Res Commun. 1990. PMID: 2390083

6

A multisubstrate adduct inhibitor of a purine biosynthetic enzyme with a picomolar dissociation constant.

Inglese J, Blatchly RA, Benkovic SJ. Inglese J, et al. Among authors: benkovic sj. J Med Chem. 1989 May;32(5):937-40. doi: 10.1021/jm00125a002. J Med Chem. 1989. PMID: 2709379 No abstract available.

7

An antibody probe to determine the native species of glycinamide ribonucleotide transformylase in chicken liver.

Young M, Sammons RD, Mueller WT, Benkovic SJ. Young M, et al. Among authors: benkovic sj. Biochemistry. 1984 Aug 14;23(17):3979-86. doi: 10.1021/bi00312a027. Biochemistry. 1984. PMID: 6386041

8

Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.

Klein C, Chen P, Arevalo JH, Stura EA, Marolewski A, Warren MS, Benkovic SJ, Wilson IA. Klein C, et al. Among authors: benkovic sj. J Mol Biol. 1995 May 26;249(1):153-75. doi: 10.1006/jmbi.1995.0286. J Mol Biol. 1995. PMID: 7776369

9

Cloning and characterization of a new purine biosynthetic enzyme: a non-folate glycinamide ribonucleotide transformylase from E. coli.

Marolewski A, Smith JM, Benkovic SJ. Marolewski A, et al. Among authors: benkovic sj. Biochemistry. 1994 Mar 8;33(9):2531-7. doi: 10.1021/bi00175a023. Biochemistry. 1994. PMID: 8117714

10

10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase.

Boger DL, Haynes NE, Kitos PA, Warren MS, Ramcharan J, Marolewski AE, Benkovic SJ. Boger DL, et al. Among authors: benkovic sj. Bioorg Med Chem. 1997 Sep;5(9):1817-30. doi: 10.1016/s0968-0896(97)00120-x. Bioorg Med Chem. 1997. PMID: 9354237

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