Funk J - Search Results

1

A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

Zeller A, Tang L, Dertinger SD, Funk J, Duran-Pacheco G, Guérard M. Zeller A, et al. Among authors: funk j. Mutagenesis. 2016 May;31(3):239-53. doi: 10.1093/mutage/gev077. Epub 2015 Nov 20. Mutagenesis. 2016. PMID: 26590612

2

Dose-response relationship of temozolomide, determined by the Pig-a, comet, and micronucleus assay.

Guérard M, Johnson G, Dertinger S, Duran-Pacheco G, Funk J, Zeller A. Guérard M, et al. Among authors: funk j. Arch Toxicol. 2017 Jun;91(6):2443-2453. doi: 10.1007/s00204-016-1923-4. Epub 2017 Feb 15. Arch Toxicol. 2017. PMID: 28197649

3

From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides.

Braendli-Baiocco A, Festag M, Dumong Erichsen K, Persson R, Mihatsch MJ, Fisker N, Funk J, Mohr S, Constien R, Ploix C, Brady K, Berrera M, Altmann B, Lenz B, Albassam M, Schmitt G, Weiser T, Schuler F, Singer T, Tessier Y. Braendli-Baiocco A, et al. Among authors: funk j. Toxicol Sci. 2017 May 1;157(1):112-128. doi: 10.1093/toxsci/kfx025. Toxicol Sci. 2017. PMID: 28123102 Free PMC article.

4

An innovative investigative approach to characterize the effects observed in a combined fertility study in male and female rats.

Xie J, Funk J, Bopst M, Ottaviani G, Downes N, Hackford S, Villabruna L, Schmitt G, Barrow P. Xie J, et al. Among authors: funk j. Regul Toxicol Pharmacol. 2018 Jun;95:339-347. doi: 10.1016/j.yrtph.2018.04.007. Epub 2018 Apr 7. Regul Toxicol Pharmacol. 2018. PMID: 29635059

5

Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.

Boess F, Lenz B, Funk J, Niederhauser U, Bassett S, Zhang JD, Singer T, Roth AB. Boess F, et al. Among authors: funk j. Toxicology. 2017 Mar 15;379:48-61. doi: 10.1016/j.tox.2017.01.018. Epub 2017 Feb 5. Toxicology. 2017. PMID: 28174063

6

Image analysis for TSH mRNA in situ hybridization in pituitary glands from rats with thyroid follicular cell hypertrophy after treatment with three different test compounds.

Funk J, Ebeling M, Singer T, Landes C. Funk J, et al. Res Vet Sci. 2017 Oct;114:313-321. doi: 10.1016/j.rvsc.2017.06.007. Epub 2017 Jun 11. Res Vet Sci. 2017. PMID: 28646742

7

Primary endothelial damage is the mechanism of cardiotoxicity of tubulin-binding drugs.

Mikaelian I, Buness A, de Vera-Mudry MC, Kanwal C, Coluccio D, Rasmussen E, Char HW, Carvajal V, Hilton H, Funk J, Hoflack JC, Fielden M, Herting F, Dunn M, Suter-Dick L. Mikaelian I, et al. Among authors: funk j. Toxicol Sci. 2010 Sep;117(1):144-51. doi: 10.1093/toxsci/kfq189. Epub 2010 Jul 12. Toxicol Sci. 2010. PMID: 20624997

8

Advanced Clinical Imaging and Tissue-based Biomarkers of the Eye for Toxicology Studies in Minipigs.

Atzpodien EA, Jacobsen B, Funk J, Altmann B, Silva Munoz MA, Singer T, Gyger C, Hasler P, Maloca P. Atzpodien EA, et al. Among authors: funk j. Toxicol Pathol. 2016 Apr;44(3):398-413. doi: 10.1177/0192623315615553. Epub 2015 Dec 16. Toxicol Pathol. 2016. PMID: 26680760

9

Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro.

Nguyen DG, Funk J, Robbins JB, Crogan-Grundy C, Presnell SC, Singer T, Roth AB. Nguyen DG, et al. Among authors: funk j. PLoS One. 2016 Jul 7;11(7):e0158674. doi: 10.1371/journal.pone.0158674. eCollection 2016. PLoS One. 2016. PMID: 27387377 Free PMC article.

10

Histopathologic findings after treatment with different oxidosqualene cyclase (OSC) inhibitors in hamsters and dogs.

Funk J, Landes C. Funk J, et al. Exp Toxicol Pathol. 2005 Aug;57(1):29-38. doi: 10.1016/j.etp.2005.02.006. Exp Toxicol Pathol. 2005. PMID: 16089317

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