Shah DK - Search Results

1

HER2/ERBB2 immunoreactivity in human retinoblastoma.

Seigel GM, Sharma S, Hackam AS, Shah DK. Seigel GM, et al. Among authors: shah dk. Tumour Biol. 2016 May;37(5):6135-42. doi: 10.1007/s13277-015-4475-y. Epub 2015 Nov 27. Tumour Biol. 2016. PMID: 26614428 Free PMC article.

2

Integration of bioanalytical measurements using PK-PD modeling and simulation: implications for antibody-drug conjugate development.

Khot A, Sharma S, Shah DK. Khot A, et al. Among authors: shah dk. Bioanalysis. 2015;7(13):1633-48. doi: 10.4155/bio.15.85. Bioanalysis. 2015. PMID: 26226312 Review.

3

Influence of molecular size on tissue distribution of antibody fragments.

Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. Li Z, et al. Among authors: shah dk. MAbs. 2016;8(1):113-9. doi: 10.1080/19420862.2015.1111497. Epub 2015 Oct 23. MAbs. 2016. PMID: 26496429 Free PMC article.

4

Quantitative characterization of in vitro bystander effect of antibody-drug conjugates.

Singh AP, Sharma S, Shah DK. Singh AP, et al. Among authors: shah dk. J Pharmacokinet Pharmacodyn. 2016 Dec;43(6):567-582. doi: 10.1007/s10928-016-9495-8. Epub 2016 Sep 26. J Pharmacokinet Pharmacodyn. 2016. PMID: 27670282 Free PMC article.

5

In situ analysis of Her2 DNA and RNA in retinoblastoma and adjacent retina.

Seigel GM, Shah DK, Mendoza P, Szalai E, Grossniklaus H, Song Y, Shan J. Seigel GM, et al. Among authors: shah dk. Oncoscience. 2019 Aug 23;6(7-8):357-366. doi: 10.18632/oncoscience.489. eCollection 2019 Jul. Oncoscience. 2019. PMID: 31608299 Free PMC article.

6

Evaluation of Quantitative Relationship Between Target Expression and Antibody-Drug Conjugate Exposure Inside Cancer Cells.

Sharma S, Li Z, Bussing D, Shah DK. Sharma S, et al. Among authors: shah dk. Drug Metab Dispos. 2020 May;48(5):368-377. doi: 10.1124/dmd.119.089276. Epub 2020 Feb 21. Drug Metab Dispos. 2020. PMID: 32086295 Free PMC article.

7

Evolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander Effect.

Singh AP, Seigel GM, Guo L, Verma A, Wong GG, Cheng HP, Shah DK. Singh AP, et al. Among authors: shah dk. J Pharmacol Exp Ther. 2020 Jul;374(1):184-199. doi: 10.1124/jpet.119.262287. Epub 2020 Apr 9. J Pharmacol Exp Ther. 2020. PMID: 32273304 Free PMC article.

8

Quantitative Evaluation of the Effect of Antigen Expression Level on Antibody-Drug Conjugate Exposure in Solid Tumor.

Bussing D, Sharma S, Li Z, Meyer LF, Shah DK. Bussing D, et al. Among authors: shah dk. AAPS J. 2021 Apr 15;23(3):56. doi: 10.1208/s12248-021-00584-y. AAPS J. 2021. PMID: 33856579

9

Effect of Size on Solid Tumor Disposition of Protein Therapeutics.

Li Z, Li Y, Chang HP, Chang HY, Guo L, Shah DK. Li Z, et al. Among authors: shah dk. Drug Metab Dispos. 2019 Oct;47(10):1136-1145. doi: 10.1124/dmd.119.087809. Epub 2019 Aug 6. Drug Metab Dispos. 2019. PMID: 31387870 Free PMC article.

10

Antibody Coadministration as a Strategy to Overcome Binding-Site Barrier for ADCs: a Quantitative Investigation.

Singh AP, Guo L, Verma A, Wong GG, Thurber GM, Shah DK. Singh AP, et al. Among authors: shah dk. AAPS J. 2020 Jan 14;22(2):28. doi: 10.1208/s12248-019-0387-x. AAPS J. 2020. PMID: 31938899 Free PMC article.

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