Rampazzo C - Search Results

1

The druggability of intracellular nucleotide-degrading enzymes.

Rampazzo C, Tozzi MG, Dumontet C, Jordheim LP. Rampazzo C, et al. Cancer Chemother Pharmacol. 2016 May;77(5):883-93. doi: 10.1007/s00280-015-2921-6. Epub 2015 Nov 27. Cancer Chemother Pharmacol. 2016. PMID: 26614508 Review.

2

Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy.

Mazzon C, Rampazzo C, Scaini MC, Gallinaro L, Karlsson A, Meier C, Balzarini J, Reichard P, Bianchi V. Mazzon C, et al. Among authors: rampazzo c. Biochem Pharmacol. 2003 Aug 1;66(3):471-9. doi: 10.1016/s0006-2952(03)00290-9. Biochem Pharmacol. 2003. PMID: 12907246

3

Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors.

Rinaldo-Matthis A, Rampazzo C, Balzarini J, Reichard P, Bianchi V, Nordlund P. Rinaldo-Matthis A, et al. Among authors: rampazzo c. Mol Pharmacol. 2004 Apr;65(4):860-7. doi: 10.1124/mol.65.4.860. Mol Pharmacol. 2004. PMID: 15044615

4

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.

Franzolin E, Pontarin G, Rampazzo C, Miazzi C, Ferraro P, Palumbo E, Reichard P, Bianchi V. Franzolin E, et al. Among authors: rampazzo c. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14272-7. doi: 10.1073/pnas.1312033110. Epub 2013 Jul 15. Proc Natl Acad Sci U S A. 2013. PMID: 23858451 Free PMC article.

5

SAMHD1 restricts the deoxyguanosine triphosphate pool contributing to telomere stability in telomerase-positive cells.

D'Aronco G, Ferraro P, Sassano V, Dagostino C, Biancotto M, Palumbo E, Presot E, Russo A, Bianchi V, Rampazzo C. D'Aronco G, et al. Among authors: rampazzo c. FASEB J. 2023 Apr;37(4):e22883. doi: 10.1096/fj.202300122R. FASEB J. 2023. PMID: 36934410

6

5'-Nucleotidases: specific assays for five different enzymes in cell extracts.

Rampazzo C, Mazzon C, Reichard P, Bianchi V. Rampazzo C, et al. Biochem Biophys Res Commun. 2002 Apr 26;293(1):258-63. doi: 10.1016/S0006-291X(02)00206-1. Biochem Biophys Res Commun. 2002. PMID: 12054593

7

Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).

Miazzi C, Ferraro P, Pontarin G, Rampazzo C, Reichard P, Bianchi V. Miazzi C, et al. Among authors: rampazzo c. J Biol Chem. 2014 Jun 27;289(26):18339-46. doi: 10.1074/jbc.M114.571091. Epub 2014 May 14. J Biol Chem. 2014. PMID: 24828500 Free PMC article.

8

SAMHD1-deficient fibroblasts from Aicardi-Goutières Syndrome patients can escape senescence and accumulate mutations.

Franzolin E, Coletta S, Ferraro P, Pontarin G, D'Aronco G, Stevanoni M, Palumbo E, Cagnin S, Bertoldi L, Feltrin E, Valle G, Russo A, Bianchi V, Rampazzo C. Franzolin E, et al. Among authors: rampazzo c. FASEB J. 2020 Jan;34(1):631-647. doi: 10.1096/fj.201902508R. Epub 2019 Nov 26. FASEB J. 2020. PMID: 31914608

9

The Deoxynucleoside Triphosphate Triphosphohydrolase Activity of SAMHD1 Protein Contributes to the Mitochondrial DNA Depletion Associated with Genetic Deficiency of Deoxyguanosine Kinase.

Franzolin E, Salata C, Bianchi V, Rampazzo C. Franzolin E, et al. Among authors: rampazzo c. J Biol Chem. 2015 Oct 23;290(43):25986-96. doi: 10.1074/jbc.M115.675082. Epub 2015 Sep 4. J Biol Chem. 2015. PMID: 26342080 Free PMC article.

10

Human mitochondrial 5'-deoxyribonucleotidase. Overproduction in cultured cells and functional aspects.

Gallinaro L, Crovatto K, Rampazzo C, Pontarin G, Ferraro P, Milanesi E, Reichard P, Bianchi V. Gallinaro L, et al. Among authors: rampazzo c. J Biol Chem. 2002 Sep 20;277(38):35080-7. doi: 10.1074/jbc.M203755200. Epub 2002 Jul 17. J Biol Chem. 2002. PMID: 12124385 Free article.

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