Francke S - Search Results

1

The role of ADME pharmacogenomics in early clinical trials: perspective of the Industry Pharmacogenomics Working Group (I-PWG).

Tremaine L, Brian W, DelMonte T, Francke S, Groenen P, Johnson K, Li L, Pearson K, Marshall JC. Tremaine L, et al. Among authors: francke s. Pharmacogenomics. 2015 Dec;16(18):2055-67. doi: 10.2217/pgs.15.141. Epub 2015 Nov 30. Pharmacogenomics. 2015. PMID: 26616152 Free PMC article. Review.

2

Case-control study of the association between select HLA genes and anti-erythropoietin antibody-positive pure red-cell aplasia.

Fijal B, Ricci D, Vercammen E, Palmer PA, Fotiou F, Fife D, Lindholm A, Broderick E, Francke S, Wu X, Colaianne J, Cohen N. Fijal B, et al. Among authors: francke s. Pharmacogenomics. 2008 Feb;9(2):157-67. doi: 10.2217/14622416.9.2.157. Pharmacogenomics. 2008. PMID: 18370845

3

In vitro metabolism of canagliflozin in human liver, kidney, intestine microsomes, and recombinant uridine diphosphate glucuronosyltransferases (UGT) and the effect of genetic variability of UGT enzymes on the pharmacokinetics of canagliflozin in humans.

Francke S, Mamidi RN, Solanki B, Scheers E, Jadwin A, Favis R, Devineni D. Francke S, et al. J Clin Pharmacol. 2015 Sep;55(9):1061-72. doi: 10.1002/jcph.506. Epub 2015 May 20. J Clin Pharmacol. 2015. PMID: 25827774

4

Effect of CYP2D6 genetic polymorphism on the population pharmacokinetics of tipifarnib.

Perez-Ruixo JJ, Zannikos P, Ozdemir V, Franc MA, Francke S, Piotrovsky V. Perez-Ruixo JJ, et al. Among authors: francke s. Cancer Chemother Pharmacol. 2006 Nov;58(5):681-91. doi: 10.1007/s00280-006-0215-8. Epub 2006 Mar 17. Cancer Chemother Pharmacol. 2006. PMID: 16544144 Clinical Trial.

5

The effect of UGT2B7*2 polymorphism on the pharmacokinetics of OROS® hydromorphone in Taiwanese subjects.

Vandenbossche J, Richards H, Francke S, Van Den Bergh A, Lu CC, Franc MA. Vandenbossche J, et al. Among authors: francke s. J Clin Pharmacol. 2014 Oct;54(10):1170-9. doi: 10.1002/jcph.305. Epub 2014 Apr 15. J Clin Pharmacol. 2014. PMID: 24706503 Clinical Trial.

6

Tramadol Hydrochloride at Steady State Lacks Clinically Relevant QTc Interval Increases in Healthy Adults.

Massarella J, Ariyawansa J, Natarajan J, Francke S, Murtaugh T, DeLemos B, Vaughan S, Fonseca S. Massarella J, et al. Among authors: francke s. Clin Pharmacol Drug Dev. 2019 Jan;8(1):95-106. doi: 10.1002/cpdd.473. Epub 2018 May 18. Clin Pharmacol Drug Dev. 2019. PMID: 29775246 Free PMC article. Clinical Trial.

7

A candidate-gene association study of topiramate-induced weight loss in obese patients with and without type 2 diabetes mellitus.

Li QS, Lenhard JM, Zhan Y, Konvicka K, Athanasiou MC, Strauss RS, Francke S. Li QS, et al. Among authors: francke s. Pharmacogenet Genomics. 2016 Feb;26(2):53-65. doi: 10.1097/FPC.0000000000000185. Pharmacogenet Genomics. 2016. PMID: 26524290

8

Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat.

Li QS, Francke S, Snoeys J, Thipphawong J, Romano G, Novak GP. Li QS, et al. Among authors: francke s. BMC Genomics. 2023 Sep 1;24(1):513. doi: 10.1186/s12864-023-09625-6. BMC Genomics. 2023. PMID: 37658353 Free PMC article.

9

Common Variants on FGD5 Increase Hazard of Mortality or Rehospitalization in Patients With Heart Failure From the ASCEND-HF Trial.

Gui H, Tang WHW, Francke S, Li J, She R, Bazeley P, Pereira NL, Adams K, Luzum JA, Connolly TM, Hernandez AF, McNaughton CD, Williams LK, Lanfear DE. Gui H, et al. Among authors: francke s. Circ Heart Fail. 2023 Sep;16(9):e010438. doi: 10.1161/CIRCHEARTFAILURE.122.010438. Epub 2023 Jul 26. Circ Heart Fail. 2023. PMID: 37725680 Free PMC article.

10

Capability Approach and Inclusion: Developing a Context Sensitive Design for Biobased Value Chains.

Asveld L, Robaey ZH, Francke S, Osseweijer P. Asveld L, et al. Among authors: francke s. J Agric Environ Ethics. 2023;36(1):6. doi: 10.1007/s10806-023-09901-1. Epub 2023 Feb 17. J Agric Environ Ethics. 2023. PMID: 36811075 Free PMC article.

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