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Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.
Coate KC, Ramnanan CJ, Smith M, Winnick JJ, Kraft G, Irimia JM, Farmer B, Donahue P, Roach PJ, Cherrington AD, Edgerton DS. Coate KC, et al. bioRxiv [Preprint]. 2023 Oct 1:2023.09.28.559999. doi: 10.1101/2023.09.28.559999. bioRxiv. 2023. Update in: Am J Physiol Endocrinol Metab. 2024 Apr 1;326(4):E428-E442. doi: 10.1152/ajpendo.00316.2023 PMID: 37808670 Free PMC article. Updated. Preprint.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606926. doi: 10.1101/2024.08.06.606926. bioRxiv. 2024. Update in: Mol Metab. 2024 Dec;90:102050. doi: 10.1016/j.molmet.2024.102050 PMID: 39149351 Free PMC article. Updated. Preprint.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. Among authors: coate kc. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice.
Zhang Y, Xie Y, Berglund ED, Coate KC, He TT, Katafuchi T, Xiao G, Potthoff MJ, Wei W, Wan Y, Yu RT, Evans RM, Kliewer SA, Mangelsdorf DJ. Zhang Y, et al. Among authors: coate kc. Elife. 2012 Oct 15;1:e00065. doi: 10.7554/eLife.00065. Elife. 2012. PMID: 23066506 Free PMC article.
Portal glucose delivery stimulates muscle but not liver protein metabolism.
Kraft G, Coate KC, Dardevet D, Farmer B, Donahue EP, Williams PE, Cherrington AD, Moore MC. Kraft G, et al. Among authors: coate kc. Am J Physiol Endocrinol Metab. 2012 Nov 15;303(10):E1202-11. doi: 10.1152/ajpendo.00140.2012. Epub 2012 Sep 25. Am J Physiol Endocrinol Metab. 2012. PMID: 23011060 Free PMC article.
FGF21 Is an Exocrine Pancreas Secretagogue.
Coate KC, Hernandez G, Thorne CA, Sun S, Le TDV, Vale K, Kliewer SA, Mangelsdorf DJ. Coate KC, et al. Cell Metab. 2017 Feb 7;25(2):472-480. doi: 10.1016/j.cmet.2016.12.004. Epub 2017 Jan 12. Cell Metab. 2017. PMID: 28089565 Free PMC article.
39 results