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Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.
Dabertrand F, Krøigaard C, Bonev AD, Cognat E, Dalsgaard T, Domenga-Denier V, Hill-Eubanks DC, Brayden JE, Joutel A, Nelson MT. Dabertrand F, et al. Among authors: nelson mt. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E796-805. doi: 10.1073/pnas.1420765112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646445 Free PMC article.
Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage.
Ratelade J, Klug NR, Lombardi D, Angelim MKSC, Dabertrand F, Domenga-Denier V, Al-Shahi Salman R, Smith C, Gerbeau JF, Nelson MT, Joutel A. Ratelade J, et al. Among authors: nelson mt. Circulation. 2020 Jun 23;141(25):2078-2094. doi: 10.1161/CIRCULATIONAHA.119.040963. Epub 2020 Mar 18. Circulation. 2020. PMID: 32183562 Free PMC article.
CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis.
Oka F, Lee JH, Yuzawa I, Li M, von Bornstaedt D, Eikermann-Haerter K, Qin T, Chung DY, Sadeghian H, Seidel JL, Imai T, Vuralli D, Platt RM, Nelson MT, Joutel A, Sakadzic S, Ayata C. Oka F, et al. Among authors: nelson mt. J Clin Invest. 2022 Apr 15;132(8):e149759. doi: 10.1172/JCI149759. J Clin Invest. 2022. PMID: 35202003 Free PMC article.
403 results