Miller LJ - Search Results

1

Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.

Desai AJ, Lam PC, Orry A, Abagyan R, Christopoulos A, Sexton PM, Miller LJ. Desai AJ, et al. Among authors: miller lj. J Med Chem. 2015 Dec 24;58(24):9562-77. doi: 10.1021/acs.jmedchem.5b01110. Epub 2015 Dec 10. J Med Chem. 2015. PMID: 26654202 Free PMC article.

2

Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity. 1. Optimization of the agonist "trigger".

Aquino CJ, Armour DR, Berman JM, Birkemo LS, Carr RA, Croom DK, Dezube M, Dougherty RW Jr, Ervin GN, Grizzle MK, Head JE, Hirst GC, James MK, Johnson MF, Miller LJ, Queen KL, Rimele TJ, Smith DN, Sugg EE. Aquino CJ, et al. Among authors: miller lj. J Med Chem. 1996 Jan 19;39(2):562-9. doi: 10.1021/jm950626d. J Med Chem. 1996. PMID: 8558528

3

Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling.

Ji Z, Hadac EM, Henne RM, Patel SA, Lybrand TP, Miller LJ. Ji Z, et al. Among authors: miller lj. J Biol Chem. 1997 Sep 26;272(39):24393-401. doi: 10.1074/jbc.272.39.24393. J Biol Chem. 1997. PMID: 9305898 Free article.

4

A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely.

Hadac EM, Ji Z, Pinon DI, Henne RM, Lybrand TP, Miller LJ. Hadac EM, et al. Among authors: miller lj. J Med Chem. 1999 Jun 17;42(12):2105-11. doi: 10.1021/jm980732q. J Med Chem. 1999. PMID: 10377216

5

Environment and mobility of a series of fluorescent reporters at the amino terminus of structurally related peptide agonists and antagonists bound to the cholecystokinin receptor.

Harikumar KG, Pinon DI, Wessels WS, Prendergast FG, Miller LJ. Harikumar KG, et al. Among authors: miller lj. J Biol Chem. 2002 May 24;277(21):18552-60. doi: 10.1074/jbc.M201164200. Epub 2002 Mar 13. J Biol Chem. 2002. PMID: 11893747 Free article.

6

Molecular basis of agonist binding to the type A cholecystokinin receptor.

Miller LJ, Lybrand TP. Miller LJ, et al. Pharmacol Toxicol. 2002 Dec;91(6):282-5. doi: 10.1034/j.1600-0773.2002.910603.x. Pharmacol Toxicol. 2002. PMID: 12688369 Review.

7

Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth.

Cheng ZJ, Harikumar KG, Holicky EL, Miller LJ. Cheng ZJ, et al. Among authors: miller lj. J Biol Chem. 2003 Dec 26;278(52):52972-9. doi: 10.1074/jbc.M310090200. Epub 2003 Oct 8. J Biol Chem. 2003. PMID: 14534299 Free article.

8

Molecular approximation between a residue in the amino-terminal region of calcitonin and the third extracellular loop of the class B G protein-coupled calcitonin receptor.

Dong M, Pinon DI, Cox RF, Miller LJ. Dong M, et al. Among authors: miller lj. J Biol Chem. 2004 Jul 23;279(30):31177-82. doi: 10.1074/jbc.M404113200. Epub 2004 May 20. J Biol Chem. 2004. PMID: 15155765 Free article.

9

Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy.

Harikumar KG, Clain J, Pinon DI, Dong M, Miller LJ. Harikumar KG, et al. Among authors: miller lj. J Biol Chem. 2005 Jan 14;280(2):1044-50. doi: 10.1074/jbc.M409480200. Epub 2004 Nov 1. J Biol Chem. 2005. PMID: 15520004 Free article.

10

Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor.

Harikumar KG, Puri V, Singh RD, Hanada K, Pagano RE, Miller LJ. Harikumar KG, et al. Among authors: miller lj. J Biol Chem. 2005 Jan 21;280(3):2176-85. doi: 10.1074/jbc.M410385200. Epub 2004 Nov 10. J Biol Chem. 2005. PMID: 15537636 Free article.

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