Velkov T - Search Results

1

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii.

Tran TB, Cheah SE, Yu HH, Bergen PJ, Nation RL, Creek DJ, Purcell A, Forrest A, Doi Y, Song J, Velkov T, Li J. Tran TB, et al. Among authors: velkov t. J Antibiot (Tokyo). 2016 Jun;69(6):415-21. doi: 10.1038/ja.2015.127. Epub 2015 Dec 16. J Antibiot (Tokyo). 2016. PMID: 26669752 Free PMC article.

2

Structure--activity relationships of polymyxin antibiotics.

Velkov T, Thompson PE, Nation RL, Li J. Velkov T, et al. J Med Chem. 2010 Mar 11;53(5):1898-916. doi: 10.1021/jm900999h. J Med Chem. 2010. PMID: 19874036 Free PMC article. Review. No abstract available.

3

Self-assembly behavior of colistin and its prodrug colistin methanesulfonate: implications for solution stability and solubilization.

Wallace SJ, Li J, Nation RL, Prankerd RJ, Velkov T, Boyd BJ. Wallace SJ, et al. Among authors: velkov t. J Phys Chem B. 2010 Apr 15;114(14):4836-40. doi: 10.1021/jp100458x. J Phys Chem B. 2010. PMID: 20302384 Free PMC article.

4

Developing an anion host for lipid A binding and antibacterial activity.

Henderson LC, Li J, Nation RL, Velkov T, Pfeffer FM. Henderson LC, et al. Among authors: velkov t. Chem Commun (Camb). 2010 May 14;46(18):3197-9. doi: 10.1039/b925135a. Epub 2010 Mar 18. Chem Commun (Camb). 2010. PMID: 20424772

5

Design, synthesis, and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions.

Soon RL, Velkov T, Chiu F, Thompson PE, Kancharla R, Roberts K, Larson I, Nation RL, Li J. Soon RL, et al. Among authors: velkov t. Anal Biochem. 2011 Feb 15;409(2):273-83. doi: 10.1016/j.ab.2010.10.033. Epub 2010 Nov 2. Anal Biochem. 2011. PMID: 21050838 Free PMC article.

6

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein.

Azad MA, Huang JX, Cooper MA, Roberts KD, Thompson PE, Nation RL, Li J, Velkov T. Azad MA, et al. Among authors: velkov t. Biochem Pharmacol. 2012 Aug 1;84(3):278-91. doi: 10.1016/j.bcp.2012.05.004. Epub 2012 May 12. Biochem Pharmacol. 2012. PMID: 22587817 Free PMC article.

7

The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic/pharmacodynamic model.

Deris ZZ, Yu HH, Davis K, Soon RL, Jacob J, Ku CK, Poudyal A, Bergen PJ, Tsuji BT, Bulitta JB, Forrest A, Paterson DL, Velkov T, Li J, Nation RL. Deris ZZ, et al. Among authors: velkov t. Antimicrob Agents Chemother. 2012 Oct;56(10):5103-12. doi: 10.1128/AAC.01064-12. Epub 2012 Jul 16. Antimicrob Agents Chemother. 2012. PMID: 22802247 Free PMC article.

8

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

Velkov T, Soon RL, Chong PL, Huang JX, Cooper MA, Azad MA, Baker MA, Thompson PE, Roberts K, Nation RL, Clements A, Strugnell RA, Li J. Velkov T, et al. Innate Immun. 2013 Jun;19(3):265-77. doi: 10.1177/1753425912459092. Epub 2012 Sep 24. Innate Immun. 2013. PMID: 23008349 Free PMC article.

9

Reverse engineering the antigenic architecture of the haemagglutinin from influenza H5N1 clade 1 and 2.2 viruses with fine epitope mapping using monoclonal antibodies.

Rockman S, Camuglia S, Vandenberg K, Ong C, Baker MA, Nation RL, Li J, Velkov T. Rockman S, et al. Among authors: velkov t. Mol Immunol. 2013 Apr;53(4):435-42. doi: 10.1016/j.molimm.2012.10.001. Epub 2012 Nov 3. Mol Immunol. 2013. PMID: 23127859

10

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

Huang JX, Cooper MA, Baker MA, Azad MA, Nation RL, Li J, Velkov T. Huang JX, et al. Among authors: velkov t. J Mol Recognit. 2012 Dec;25(12):642-56. doi: 10.1002/jmr.2221. J Mol Recognit. 2012. PMID: 23192962 Free PMC article.

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