Guzman ML - Search Results

1

In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche.

Zong H, Sen S, Zhang G, Mu C, Albayati ZF, Gorenstein DG, Liu X, Ferrari M, Crooks PA, Roboz GJ, Shen H, Guzman ML. Zong H, et al. Among authors: guzman ml. Leukemia. 2016 Jul;30(7):1582-6. doi: 10.1038/leu.2015.343. Epub 2015 Dec 16. Leukemia. 2016. PMID: 26669973 Free PMC article. No abstract available.

2

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells.

Jordan CT, Upchurch D, Szilvassy SJ, Guzman ML, Howard DS, Pettigrew AL, Meyerrose T, Rossi R, Grimes B, Rizzieri DA, Luger SM, Phillips GL. Jordan CT, et al. Among authors: guzman ml. Leukemia. 2000 Oct;14(10):1777-84. doi: 10.1038/sj.leu.2401903. Leukemia. 2000. PMID: 11021753

3

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.

Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. Guzman ML, et al. Blood. 2007 Dec 15;110(13):4427-35. doi: 10.1182/blood-2007-05-090621. Epub 2007 Sep 5. Blood. 2007. PMID: 17804695 Free PMC article.

4

Monoclonal antibodies against IREM-1: potential for targeted therapy of AML.

Korver W, Zhao X, Singh S, Pardoux C, Zhao J, Guzman ML, Sen S, Yonkovich S, Liu S, Zhan X, Tomasevic N, Zhou C, Gros D, Jordan CT, Gotlib J, Hsi ED, Abo A. Korver W, et al. Among authors: guzman ml. Leukemia. 2009 Sep;23(9):1587-97. doi: 10.1038/leu.2009.99. Epub 2009 May 14. Leukemia. 2009. PMID: 19440216

5

Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1).

Neelakantan S, Nasim S, Guzman ML, Jordan CT, Crooks PA. Neelakantan S, et al. Among authors: guzman ml. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4346-9. doi: 10.1016/j.bmcl.2009.05.092. Epub 2009 May 27. Bioorg Med Chem Lett. 2009. PMID: 19505822

6

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.

Hassane DC, Sen S, Minhajuddin M, Rossi RM, Corbett CA, Balys M, Wei L, Crooks PA, Guzman ML, Jordan CT. Hassane DC, et al. Among authors: guzman ml. Blood. 2010 Dec 23;116(26):5983-90. doi: 10.1182/blood-2010-04-278044. Epub 2010 Oct 1. Blood. 2010. PMID: 20889920 Free article.

7

Acute myeloid leukemia stem cells: seek and destroy.

Roboz GJ, Guzman M. Roboz GJ, et al. Expert Rev Hematol. 2009 Dec;2(6):663-72. doi: 10.1586/ehm.09.53. Expert Rev Hematol. 2009. PMID: 21082958 Free PMC article. Review.

8

Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture.

Nasim S, Guzman ML, Jordan CT, Crooks PA. Nasim S, et al. Among authors: guzman ml. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4879-83. doi: 10.1016/j.bmcl.2011.06.027. Epub 2011 Jun 22. Bioorg Med Chem Lett. 2011. PMID: 21757349 Free PMC article.

9

Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy.

Taldone T, Gomes-DaGama EM, Zong H, Sen S, Alpaugh ML, Zatorska D, Alonso-Sabadell R, Guzman ML, Chiosis G. Taldone T, et al. Among authors: guzman ml. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5347-52. doi: 10.1016/j.bmcl.2011.07.026. Epub 2011 Jul 14. Bioorg Med Chem Lett. 2011. PMID: 21802945 Free PMC article.

10

Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML. Sen S, et al. Among authors: guzman ml. Exp Hematol. 2013 Sep;41(9):799-807.e4. doi: 10.1016/j.exphem.2013.04.012. Epub 2013 May 6. Exp Hematol. 2013. PMID: 23660068 Free PMC article. Clinical Trial.

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