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EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA. Wu Y, et al. Among authors: srinivasan g. PLoS Genet. 2015 Dec 18;11(12):e1005675. doi: 10.1371/journal.pgen.1005675. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26684013 Free PMC article.
Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA. Kim HS, et al. Among authors: srinivasan g. J Biol Chem. 2017 Feb 17;292(7):2795-2804. doi: 10.1074/jbc.M116.758235. Epub 2017 Jan 3. J Biol Chem. 2017. PMID: 28049724 Free PMC article.
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.
Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R. Srinivasan G, et al. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17438-17443. doi: 10.1073/pnas.1903150116. Epub 2019 Aug 8. Proc Natl Acad Sci U S A. 2019. PMID: 31395736 Free PMC article.
The splicing component ISY1 regulates APE1 in base excision repair.
Jaiswal AS, Williamson EA, Srinivasan G, Kong K, Lomelino CL, McKenna R, Walter C, Sung P, Narayan S, Hromas R. Jaiswal AS, et al. Among authors: srinivasan g. DNA Repair (Amst). 2020 Feb;86:102769. doi: 10.1016/j.dnarep.2019.102769. Epub 2019 Dec 13. DNA Repair (Amst). 2020. PMID: 31887540 Free PMC article.
Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.
Srinivasan G, Sidhu GS, Williamson EA, Jaiswal AS, Najmunnisa N, Wilcoxen K, Jones D, George TJ Jr, Hromas R. Srinivasan G, et al. Cancer Chemother Pharmacol. 2017 Oct;80(4):861-867. doi: 10.1007/s00280-017-3401-y. Epub 2017 Jul 29. Cancer Chemother Pharmacol. 2017. PMID: 28756516 Free PMC article.
308 results