Siegel DL - Search Results

1

A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.

Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska MA, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M. Fuentes RE, et al. Among authors: siegel dl. J Clin Invest. 2016 Feb;126(2):483-94. doi: 10.1172/JCI81470. J Clin Invest. 2016. PMID: 26690701 Free PMC article.

2

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.

Pickens B, Mao Y, Li D, Siegel DL, Poncz M, Cines DB, Zheng XL. Pickens B, et al. Among authors: siegel dl. Blood. 2015 May 21;125(21):3326-34. doi: 10.1182/blood-2014-07-587139. Epub 2015 Mar 23. Blood. 2015. PMID: 25800050 Free PMC article.

3

Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond.

Villa CH, Cines DB, Siegel DL, Muzykantov V. Villa CH, et al. Among authors: siegel dl. Transfus Med Rev. 2017 Jan;31(1):26-35. doi: 10.1016/j.tmrv.2016.08.004. Epub 2016 Aug 17. Transfus Med Rev. 2017. PMID: 27707522 Free PMC article. Review.

4

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes.

Villa CH, Pan DC, Johnston IH, Greineder CF, Walsh LR, Hood ED, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Villa CH, et al. Among authors: siegel dl. Blood Adv. 2018 Feb 13;2(3):165-176. doi: 10.1182/bloodadvances.2017011734. Blood Adv. 2018. PMID: 29365311 Free PMC article.

5

Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury.

Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR. Carnemolla R, et al. Among authors: siegel dl. FASEB J. 2017 Feb;31(2):761-770. doi: 10.1096/fj.201600912R. Epub 2016 Nov 11. FASEB J. 2017. PMID: 27836986 Free PMC article.

6

Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier.

Villa CH, Pan DC, Zaitsev S, Cines DB, Siegel DL, Muzykantov VR. Villa CH, et al. Among authors: siegel dl. Ther Deliv. 2015 Jul;6(7):795-826. doi: 10.4155/tde.15.34. Ther Deliv. 2015. PMID: 26228773 Free PMC article. Review.

7

ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model.

Ostertag EM, Bdeir K, Kacir S, Thiboutot M, Gulendran G, Yunk L, Hayes VM, Motto DG, Poncz M, Zheng XL, Cines DB, Siegel DL. Ostertag EM, et al. Among authors: siegel dl. Transfusion. 2016 Jul;56(7):1775-85. doi: 10.1111/trf.13583. Epub 2016 Apr 4. Transfusion. 2016. PMID: 27040023 Free PMC article.

8

Mechanisms of action of therapeutics in idiopathic thrombocytopenic purpura.

Cines DB, McKenzie SE, Siegel DL. Cines DB, et al. Among authors: siegel dl. J Pediatr Hematol Oncol. 2003 Dec;25 Suppl 1:S52-6. doi: 10.1097/00043426-200312001-00012. J Pediatr Hematol Oncol. 2003. PMID: 14668641 Review.

9

Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation.

Roark JH, Bussel JB, Cines DB, Siegel DL. Roark JH, et al. Among authors: siegel dl. Blood. 2002 Aug 15;100(4):1388-98. Blood. 2002. PMID: 12149222 Free article.

10

Pathologically stiff erythrocytes impede contraction of blood clots.

Tutwiler V, Litvinov RI, Protopopova A, Nagaswami C, Villa C, Woods E, Abdulmalik O, Siegel DL, Russell JE, Muzykantov VR, Lam WA, Myers DR, Weisel JW. Tutwiler V, et al. Among authors: siegel dl. J Thromb Haemost. 2021 Aug;19(8):1990-2001. doi: 10.1111/jth.15407. Epub 2021 Jul 7. J Thromb Haemost. 2021. PMID: 34233380 Free PMC article.

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