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Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.
Geeven G, Zhu Y, Kim BJ, Bartholdy BA, Yang SM, Macfarlan TS, Gifford WD, Pfaff SL, Verstegen MJ, Pinto H, Vermunt MW, Creyghton MP, Wijchers PJ, Stamatoyannopoulos JA, Skoultchi AI, de Laat W. Geeven G, et al. Among authors: skoultchi ai. Genome Biol. 2015 Dec 23;16:289. doi: 10.1186/s13059-015-0857-0. Genome Biol. 2015. PMID: 26700097 Free PMC article.
H1 histones control the epigenetic landscape by local chromatin compaction.
Willcockson MA, Healton SE, Weiss CN, Bartholdy BA, Botbol Y, Mishra LN, Sidhwani DS, Wilson TJ, Pinto HB, Maron MI, Skalina KA, Toro LN, Zhao J, Lee CH, Hou H, Yusufova N, Meydan C, Osunsade A, David Y, Cesarman E, Melnick AM, Sidoli S, Garcia BA, Edelmann W, Macian F, Skoultchi AI. Willcockson MA, et al. Among authors: skoultchi ai. Nature. 2021 Jan;589(7841):293-298. doi: 10.1038/s41586-020-3032-z. Epub 2020 Dec 9. Nature. 2021. PMID: 33299182 Free PMC article.
Global chromatin compaction limits the strength of the DNA damage response.
Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O. Murga M, et al. Among authors: skoultchi ai. J Cell Biol. 2007 Sep 24;178(7):1101-8. doi: 10.1083/jcb.200704140. J Cell Biol. 2007. PMID: 17893239 Free PMC article.
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
Healton SE, Pinto HD, Mishra LN, Hamilton GA, Wheat JC, Swist-Rosowska K, Shukeir N, Dou Y, Steidl U, Jenuwein T, Gamble MJ, Skoultchi AI. Healton SE, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14251-14258. doi: 10.1073/pnas.1920725117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513732 Free PMC article.
144 results