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Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase.
Sari-Hassoun M, Clement MJ, Hamdi I, Bollot G, Bauvais C, Joshi V, Toma F, Burgo A, Cailleret M, Rosales-Hernández MC, Macias Pérez ME, Chabane-Sari D, Curmi PA. Sari-Hassoun M, et al. Biochem Pharmacol. 2016 Feb 15;102:45-63. doi: 10.1016/j.bcp.2015.12.013. Epub 2015 Dec 18. Biochem Pharmacol. 2016. PMID: 26707799
Aromatic Regions Govern the Recognition of NADPH Oxidase Inhibitors as Diapocynin and its Analogues.
Macías Pérez ME, Hernández Rodríguez M, Cabrera Pérez LC, Fragoso-Vázquez MJ, Correa-Basurto J, Padilla-Martínez II, Méndez Luna D, Mera Jiménez E, Flores Sandoval C, Tamay Cach F, Rosales-Hernández MC. Macías Pérez ME, et al. Arch Pharm (Weinheim). 2017 Oct;350(10). doi: 10.1002/ardp.201700041. Epub 2017 Aug 21. Arch Pharm (Weinheim). 2017. PMID: 28833480
Molecular modeling applied to anti-cancer drug development.
Rosales-Hernandez MC, Bermúdez-Lugo J, Garcia J, Trujillo-Ferrara J, Correa-Basurto J. Rosales-Hernandez MC, et al. Anticancer Agents Med Chem. 2009 Feb;9(2):230-8. doi: 10.2174/187152009787313819. Anticancer Agents Med Chem. 2009. PMID: 19199867 Review.
Exploring the biotransformation of N-(2-hydroxyphenyl)-2-propylpentanamide (an aryl valproic acid derivative) by CYP2C11, using in silico predictions and in vitro studies.
Mendieta-Wejebe JE, Silva-Trujillo A, Bello M, Mendoza-Figueroa HL, Galindo-Alvarez NL, Albores A, Tamay-Cach F, Rosales-Hernández MC, Romero-Castro A, Correa-Basurto J. Mendieta-Wejebe JE, et al. J Pharm Pharmacol. 2020 Jul;72(7):938-955. doi: 10.1111/jphp.13270. Epub 2020 Apr 19. J Pharm Pharmacol. 2020. PMID: 32307724
80 results