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Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation.
Bhatt JM, Viktorova EG, Busby T, Wyrozumska P, Newman LE, Lin H, Lee E, Wright J, Belov GA, Kahn RA, Sztul E. Bhatt JM, et al. Among authors: viktorova eg. Am J Physiol Cell Physiol. 2016 Mar 15;310(6):C456-69. doi: 10.1152/ajpcell.00185.2015. Epub 2015 Dec 30. Am J Physiol Cell Physiol. 2016. PMID: 26718629 Free PMC article.
Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity.
Pocognoni CA, Viktorova EG, Wright J, Meissner JM, Sager G, Lee E, Belov GA, Sztul E. Pocognoni CA, et al. Among authors: viktorova eg. Am J Physiol Cell Physiol. 2018 Jun 1;314(6):C675-C689. doi: 10.1152/ajpcell.00221.2017. Epub 2018 Feb 14. Am J Physiol Cell Physiol. 2018. PMID: 29443553 Free PMC article.
35 results