Roberts AG - Search Results

1

The role of cytochrome P450 BM3 phenylalanine-87 and threonine-268 in binding organic hydroperoxides.

Roberts AG, Katayama J, Kaspera R, Ledwitch KV, Le Trong I, Stenkamp RE, Thompson JA, Totah RA. Roberts AG, et al. Biochim Biophys Acta. 2016 Apr;1860(4):669-77. doi: 10.1016/j.bbagen.2015.12.014. Epub 2015 Dec 23. Biochim Biophys Acta. 2016. PMID: 26723172

2

Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein.

Ledwitch KV, Barnes RW, Roberts AG. Ledwitch KV, et al. Among authors: roberts ag. Biosci Rep. 2016 Jan 28;36(2):e00309. doi: 10.1042/BSR20150317. Biosci Rep. 2016. PMID: 26823559 Free PMC article.

3

Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein.

Ledwitch KV, Gibbs ME, Barnes RW, Roberts AG. Ledwitch KV, et al. Among authors: roberts ag. Biochem Pharmacol. 2016 Oct 15;118:96-108. doi: 10.1016/j.bcp.2016.08.013. Epub 2016 Aug 13. Biochem Pharmacol. 2016. PMID: 27531061 Free PMC article.

4

Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein.

Ledwitch KV, Roberts AG. Ledwitch KV, et al. Among authors: roberts ag. AAPS J. 2017 Mar;19(2):409-420. doi: 10.1208/s12248-016-0023-y. Epub 2016 Dec 27. AAPS J. 2017. PMID: 28028729 Free PMC article. Review.

5

Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter.

Karasik A, Ledwitch KV, Arányi T, Váradi A, Roberts A, Szeri F. Karasik A, et al. FASEB J. 2018 Feb;32(2):669-680. doi: 10.1096/fj.201700606R. Epub 2018 Jan 4. FASEB J. 2018. PMID: 28939593 Free PMC article.

6

A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein.

Gibbs ME, Wilt LA, Ledwitch KV, Roberts AG. Gibbs ME, et al. Among authors: roberts ag. J Pharm Sci. 2018 Jul;107(7):1937-1947. doi: 10.1016/j.xphs.2018.02.019. Epub 2018 Feb 28. J Pharm Sci. 2018. PMID: 29499278 Free PMC article.

7

The conformation and dynamics of P-glycoprotein in a lipid bilayer investigated by atomic force microscopy.

Sigdel KP, Wilt LA, Marsh BP, Roberts AG, King GM. Sigdel KP, et al. Among authors: roberts ag. Biochem Pharmacol. 2018 Oct;156:302-311. doi: 10.1016/j.bcp.2018.08.017. Epub 2018 Aug 16. Biochem Pharmacol. 2018. PMID: 30121251 Free PMC article.

8

The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences.

Nguyen PH, Sigdel KP, Schaefer KG, Mensah GAK, King GM, Roberts AG. Nguyen PH, et al. Among authors: roberts ag. Biochem Pharmacol. 2020 Apr;174:113813. doi: 10.1016/j.bcp.2020.113813. Epub 2020 Jan 16. Biochem Pharmacol. 2020. PMID: 31954717 Free PMC article.

9

The Structure and Mechanism of Drug Transporters.

Roberts AG. Roberts AG. Methods Mol Biol. 2021;2342:193-234. doi: 10.1007/978-1-0716-1554-6_8. Methods Mol Biol. 2021. PMID: 34272696 Free PMC article.

10

Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond.

Roberts AG, Stevens JC, Szklarz GD, Scott EE, Kumar S, Shah MB, Halpert JR. Roberts AG, et al. Drug Metab Dispos. 2023 Jan;51(1):111-122. doi: 10.1124/dmd.122.001109. Epub 2022 Oct 30. Drug Metab Dispos. 2023. PMID: 36310033 Free PMC article. Review.

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