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Page 1
A specific mutation in TBL1XR1 causes Pierpont syndrome.
Heinen CA, Jongejan A, Watson PJ, Redeker B, Boelen A, Boudzovitch-Surovtseva O, Forzano F, Hordijk R, Kelley R, Olney AH, Pierpont ME, Schaefer GB, Stewart F, van Trotsenburg AS, Fliers E, Schwabe JW, Hennekam RC. Heinen CA, et al. Among authors: jongejan a. J Med Genet. 2016 May;53(5):330-7. doi: 10.1136/jmedgenet-2015-103233. Epub 2016 Jan 14. J Med Genet. 2016. PMID: 26769062 Free PMC article.
Understanding repertoire sequencing data through a multiscale computational model of the germinal center.
García-Valiente R, Merino Tejero E, Stratigopoulou M, Balashova D, Jongejan A, Lashgari D, Pélissier A, Caniels TG, Claireaux MAF, Musters A, van Gils MJ, Rodríguez Martínez M, de Vries N, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC. García-Valiente R, et al. Among authors: jongejan a. NPJ Syst Biol Appl. 2023 Mar 16;9(1):8. doi: 10.1038/s41540-023-00271-y. NPJ Syst Biol Appl. 2023. PMID: 36927990 Free PMC article.
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.
Tammaro A, Daniels EG, Hu IM, 't Hart KC, Reid K, Juni RP, Butter LM, Vasam G, Kamble R, Jongejan A, Aviv RI, Roelofs JJTH, Aronica E, Boon RA, Menzies KJ, Houtkooper RH, Janssens GE. Tammaro A, et al. Among authors: jongejan a. iScience. 2023 Dec 12;27(1):108681. doi: 10.1016/j.isci.2023.108681. eCollection 2024 Jan 19. iScience. 2023. PMID: 38269100 Free PMC article.
CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids.
Buck TM, Quinn PMJ, Pellissier LP, Mulder AA, Jongejan A, Lu X, Boon N, Koot D, Almushattat H, Arendzen CH, Vos RM, Bradley EJ, Freund C, Mikkers HMM, Boon CJF, Moerland PD, Baas F, Koster AJ, Neefjes J, Berlin I, Jost CR, Wijnholds J. Buck TM, et al. Among authors: jongejan a. Stem Cell Reports. 2023 Sep 12;18(9):1793-1810. doi: 10.1016/j.stemcr.2023.07.001. Epub 2023 Aug 3. Stem Cell Reports. 2023. PMID: 37541258 Free PMC article.
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise.
Janssens GE, Molenaars M, Herzog K, Grevendonk L, Remie CME, Vervaart MAT, Elfrink HL, Wever EJM, Schomakers BV, Denis SW, Waterham HR, Pras-Raves ML, van Weeghel M, van Kampen AHC, Tammaro A, Butter LM, van der Rijt S, Florquin S, Jongejan A, Moerland PD, Hoeks J, Schrauwen P, Vaz FM, Houtkooper RH. Janssens GE, et al. Among authors: jongejan a. Nat Aging. 2024 May;4(5):681-693. doi: 10.1038/s43587-024-00595-2. Epub 2024 Apr 12. Nat Aging. 2024. PMID: 38609524
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM. Vacondio D, et al. Among authors: jongejan a. Cell Death Dis. 2023 Nov 28;14(11):781. doi: 10.1038/s41419-023-06316-8. Cell Death Dis. 2023. PMID: 38016947 Free PMC article.
SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma.
Leeksma AC, Derks IAM, Garrick B, Jongejan A, Colombo M, Bloedjes T, Trowe T, Leisten JC, Howarth M, Malek M, Mortensen DS, Blease K, Groza MC, Narla RK, Loos R, Kersten MJ, Moerland PD, Guikema JEJ, Kater AP, Eldering E, Filvaroff EH. Leeksma AC, et al. Among authors: jongejan a. Mol Oncol. 2023 Feb;17(2):284-297. doi: 10.1002/1878-0261.13343. Epub 2022 Dec 16. Mol Oncol. 2023. PMID: 36400430 Free PMC article.
128 results