Kumer SC - Search Results

1

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury.

Wang S, Ni HM, Dorko K, Kumer SC, Schmitt TM, Nawabi A, Komatsu M, Huang H, Ding WX. Wang S, et al. Among authors: kumer sc. Oncotarget. 2016 Apr 5;7(14):17681-98. doi: 10.18632/oncotarget.6893. Oncotarget. 2016. PMID: 26769846 Free PMC article.

2

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Xie Y, McGill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H. Xie Y, et al. Among authors: kumer sc. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):266-274. doi: 10.1016/j.taap.2014.05.010. Epub 2014 Jun 3. Toxicol Appl Pharmacol. 2014. PMID: 24905542 Free PMC article.

3

Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.

Xie Y, McGill MR, Du K, Dorko K, Kumer SC, Schmitt TM, Ding WX, Jaeschke H. Xie Y, et al. Among authors: kumer sc. Toxicol Appl Pharmacol. 2015 Dec 1;289(2):213-22. doi: 10.1016/j.taap.2015.09.022. Epub 2015 Sep 30. Toxicol Appl Pharmacol. 2015. PMID: 26431796 Free PMC article.

4

Microcystin-LR induced liver injury in mice and in primary human hepatocytes is caused by oncotic necrosis.

Woolbright BL, Williams CD, Ni H, Kumer SC, Schmitt T, Kane B, Jaeschke H. Woolbright BL, et al. Among authors: kumer sc. Toxicon. 2017 Jan;125:99-109. doi: 10.1016/j.toxicon.2016.11.254. Epub 2016 Nov 23. Toxicon. 2017. PMID: 27889601 Free PMC article.

5

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.

Wang S, Ni HM, Chao X, Wang H, Bridges B, Kumer S, Schmitt T, Mareninova O, Gukovskaya A, De Lisle RC, Ballabio A, Pacher P, Ding WX. Wang S, et al. Autophagy. 2019 Nov;15(11):1954-1969. doi: 10.1080/15548627.2019.1596486. Epub 2019 Mar 30. Autophagy. 2019. PMID: 30894069 Free PMC article.

6

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

Woolbright BL, Dorko K, Antoine DJ, Clarke JI, Gholami P, Li F, Kumer SC, Schmitt TM, Forster J, Fan F, Jenkins RE, Park BK, Hagenbuch B, Olyaee M, Jaeschke H. Woolbright BL, et al. Among authors: kumer sc. Toxicol Appl Pharmacol. 2015 Mar 15;283(3):168-77. doi: 10.1016/j.taap.2015.01.015. Epub 2015 Jan 28. Toxicol Appl Pharmacol. 2015. PMID: 25636263 Free PMC article.

7

Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H. Xie Y, et al. Among authors: kumer sc. J Clin Transl Res. 2015;1(2):100-106. doi: 10.18053/jctres.201502.004. Epub 2015 Sep 30. J Clin Transl Res. 2015. PMID: 26722668 Free PMC article.

8

Lack of direct cytotoxicity of extracellular ATP against hepatocytes: role in the mechanism of acetaminophen hepatotoxicity.

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H. Xie Y, et al. Among authors: kumer sc. J Clin Transl Res. 2015 Sep 30;1(2):1-7. eCollection 2015 Sep 30. J Clin Transl Res. 2015. PMID: 30873447 Free PMC article.

9

Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver.

Chavan H, Li F, Tessman R, Mickey K, Dorko K, Schmitt T, Kumer S, Gunewardena S, Gaikwad N, Krishnamurthy P. Chavan H, et al. J Biol Chem. 2015 Mar 20;290(12):7871-86. doi: 10.1074/jbc.M114.605386. Epub 2015 Jan 26. J Biol Chem. 2015. PMID: 25623066 Free PMC article.

10

Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice.

Zhao J, Adams A, Roberts B, O'Neil M, Vittal A, Schmitt T, Kumer S, Cox J, Li Z, Weinman SA, Tikhanovich I. Zhao J, et al. Hepatology. 2018 Mar;67(3):1109-1126. doi: 10.1002/hep.29587. Epub 2018 Jan 24. Hepatology. 2018. PMID: 29023917 Free PMC article.

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