D'Oro U - Search Results

1

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens.

Knudsen NP, Olsen A, Buonsanti C, Follmann F, Zhang Y, Coler RN, Fox CB, Meinke A, D'Oro U, Casini D, Bonci A, Billeskov R, De Gregorio E, Rappuoli R, Harandi AM, Andersen P, Agger EM. Knudsen NP, et al. Sci Rep. 2016 Jan 21;6:19570. doi: 10.1038/srep19570. Sci Rep. 2016. PMID: 26791076 Free PMC article.

2

Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders.

Rosa D, Saletti G, De Gregorio E, Zorat F, Comar C, D'Oro U, Nuti S, Houghton M, Barnaba V, Pozzato G, Abrignani S. Rosa D, et al. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18544-9. doi: 10.1073/pnas.0509402102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339892 Free PMC article.

3

Immunology of TLR-independent vaccine adjuvants.

De Gregorio E, D'Oro U, Wack A. De Gregorio E, et al. Curr Opin Immunol. 2009 Jun;21(3):339-45. doi: 10.1016/j.coi.2009.05.003. Epub 2009 Jun 1. Curr Opin Immunol. 2009. PMID: 19493664 Review.

4

Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists.

Kuka M, Baronio R, Valentini S, Monaci E, Muzzi A, Aprea S, De Gregorio E, D'Oro U. Kuka M, et al. PLoS One. 2010 Jul 9;5(7):e11491. doi: 10.1371/journal.pone.0011491. PLoS One. 2010. PMID: 20634889 Free PMC article.

5

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.

Seubert A, Calabro S, Santini L, Galli B, Genovese A, Valentini S, Aprea S, Colaprico A, D'Oro U, Giuliani MM, Pallaoro M, Pizza M, O'Hagan DT, Wack A, Rappuoli R, De Gregorio E. Seubert A, et al. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11169-74. doi: 10.1073/pnas.1107941108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690334 Free PMC article.

6

Rational design of small molecules as vaccine adjuvants.

Wu TY, Singh M, Miller AT, De Gregorio E, Doro F, D'Oro U, Skibinski DA, Mbow ML, Bufali S, Herman AE, Cortez A, Li Y, Nayak BP, Tritto E, Filippi CM, Otten GR, Brito LA, Monaci E, Li C, Aprea S, Valentini S, Calabrό S, Laera D, Brunelli B, Caproni E, Malyala P, Panchal RG, Warren TK, Bavari S, O'Hagan DT, Cooke MP, Valiante NM. Wu TY, et al. Sci Transl Med. 2014 Nov 19;6(263):263ra160. doi: 10.1126/scitranslmed.3009980. Sci Transl Med. 2014. PMID: 25411473

7

Vaccine adjuvant MF59 promotes retention of unprocessed antigen in lymph node macrophage compartments and follicular dendritic cells.

Cantisani R, Pezzicoli A, Cioncada R, Malzone C, De Gregorio E, D'Oro U, Piccioli D. Cantisani R, et al. J Immunol. 2015 Feb 15;194(4):1717-25. doi: 10.4049/jimmunol.1400623. Epub 2015 Jan 14. J Immunol. 2015. PMID: 25589069

8

A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells.

Santone M, Aprea S, Wu TY, Cooke MP, Mbow ML, Valiante NM, Rush JS, Dougan S, Avalos A, Ploegh H, De Gregorio E, Buonsanti C, D'Oro U. Santone M, et al. Hum Vaccin Immunother. 2015;11(8):2038-50. doi: 10.1080/21645515.2015.1027467. Hum Vaccin Immunother. 2015. PMID: 26024409 Free PMC article.

9

CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes.

Lazzaro S, Giovani C, Mangiavacchi S, Magini D, Maione D, Baudner B, Geall AJ, De Gregorio E, D'Oro U, Buonsanti C. Lazzaro S, et al. Immunology. 2015 Oct;146(2):312-26. doi: 10.1111/imm.12505. Epub 2015 Aug 28. Immunology. 2015. PMID: 26173587 Free PMC article.

10

Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design.

Rappuoli R, Bottomley MJ, D'Oro U, Finco O, De Gregorio E. Rappuoli R, et al. J Exp Med. 2016 Apr 4;213(4):469-81. doi: 10.1084/jem.20151960. Epub 2016 Mar 28. J Exp Med. 2016. PMID: 27022144 Free PMC article. Review.

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