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2,133 results

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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity.
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, Hutton ML, O'Neill MJ. Ahmed Z, et al. Acta Neuropathol. 2014 May;127(5):667-83. doi: 10.1007/s00401-014-1254-6. Epub 2014 Feb 16. Acta Neuropathol. 2014. PMID: 24531916 Free PMC article.
In vivo imaging of tau pathology using multi-parametric quantitative MRI.
Wells JA, O'Callaghan JM, Holmes HE, Powell NM, Johnson RA, Siow B, Torrealdea F, Ismail O, Walker-Samuel S, Golay X, Rega M, Richardson S, Modat M, Cardoso MJ, Ourselin S, Schwarz AJ, Ahmed Z, Murray TK, O'Neill MJ, Collins EC, Colgan N, Lythgoe MF. Wells JA, et al. Among authors: ahmed z. Neuroimage. 2015 May 1;111:369-78. doi: 10.1016/j.neuroimage.2015.02.023. Epub 2015 Feb 17. Neuroimage. 2015. PMID: 25700953 Free PMC article.
Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease.
Colgan N, Siow B, O'Callaghan JM, Harrison IF, Wells JA, Holmes HE, Ismail O, Richardson S, Alexander DC, Collins EC, Fisher EM, Johnson R, Schwarz AJ, Ahmed Z, O'Neill MJ, Murray TK, Zhang H, Lythgoe MF. Colgan N, et al. Among authors: ahmed z. Neuroimage. 2016 Jan 15;125:739-744. doi: 10.1016/j.neuroimage.2015.10.043. Epub 2015 Oct 23. Neuroimage. 2016. PMID: 26505297 Free PMC article.
Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease.
O'Callaghan J, Holmes H, Powell N, Wells JA, Ismail O, Harrison IF, Siow B, Johnson R, Ahmed Z, Fisher A, Meftah S, O'Neill MJ, Murray TK, Collins EC, Shmueli K, Lythgoe MF. O'Callaghan J, et al. Among authors: ahmed z. Neuroimage. 2017 Oct 1;159:334-345. doi: 10.1016/j.neuroimage.2017.08.003. Epub 2017 Aug 4. Neuroimage. 2017. PMID: 28797738 Free PMC article.
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB. Wang H, et al. Among authors: ahmed z. Mol Neurodegener. 2018 Dec 17;13(1):65. doi: 10.1186/s13024-018-0296-y. Mol Neurodegener. 2018. PMID: 30558641 Free PMC article.
Imbalance in the response of pre- and post-synaptic components to amyloidopathy.
Stephen TL, Tamagnini F, Piegsa J, Sung K, Harvey J, Oliver-Evans A, Murray TK, Ahmed Z, Hutton ML, Randall A, O'Neill MJ, Jackson JS. Stephen TL, et al. Among authors: ahmed z. Sci Rep. 2019 Oct 16;9(1):14837. doi: 10.1038/s41598-019-50781-1. Sci Rep. 2019. PMID: 31619689 Free PMC article.
Transcriptional Signatures of Tau and Amyloid Neuropathology.
Castanho I, Murray TK, Hannon E, Jeffries A, Walker E, Laing E, Baulf H, Harvey J, Bradshaw L, Randall A, Moore K, O'Neill P, Lunnon K, Collier DA, Ahmed Z, O'Neill MJ, Mill J. Castanho I, et al. Among authors: ahmed z. Cell Rep. 2020 Feb 11;30(6):2040-2054.e5. doi: 10.1016/j.celrep.2020.01.063. Cell Rep. 2020. PMID: 32049030 Free PMC article.
Impaired glymphatic function and clearance of tau in an Alzheimer's disease model.
Harrison IF, Ismail O, Machhada A, Colgan N, Ohene Y, Nahavandi P, Ahmed Z, Fisher A, Meftah S, Murray TK, Ottersen OP, Nagelhus EA, O'Neill MJ, Wells JA, Lythgoe MF. Harrison IF, et al. Among authors: ahmed z. Brain. 2020 Aug 1;143(8):2576-2593. doi: 10.1093/brain/awaa179. Brain. 2020. PMID: 32705145 Free PMC article.
2,133 results