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Hif1α is required for osteoclast activation and bone loss in male osteoporosis.
Tando T, Sato Y, Miyamoto K, Morita M, Kobayashi T, Funayama A, Kanaji A, Hao W, Watanabe R, Oike T, Nakamura M, Matsumoto M, Toyama Y, Miyamoto T. Tando T, et al. Among authors: hao w. Biochem Biophys Res Commun. 2016 Feb 5;470(2):391-396. doi: 10.1016/j.bbrc.2016.01.033. Epub 2016 Jan 11. Biochem Biophys Res Commun. 2016. PMID: 26792721
PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.
Yoshida S, Iwasaki R, Kawana H, Miyauchi Y, Hoshi H, Miyamoto H, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Kobayashi T, Sato Y, Miyamoto K, Morioka H, Matsumoto M, Chiba K, Toyama Y, Nakagawa T, Miyamoto T. Yoshida S, et al. Among authors: hao w. Biochem Biophys Res Commun. 2012 May 18;421(4):785-9. doi: 10.1016/j.bbrc.2012.04.084. Epub 2012 Apr 23. Biochem Biophys Res Commun. 2012. PMID: 22554514
HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.
Miyauchi Y, Sato Y, Kobayashi T, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Miyamoto K, Tando T, Morioka H, Matsumoto M, Chambon P, Johnson RS, Kato S, Toyama Y, Miyamoto T. Miyauchi Y, et al. Among authors: hao w. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16568-73. doi: 10.1073/pnas.1308755110. Epub 2013 Sep 10. Proc Natl Acad Sci U S A. 2013. PMID: 24023068 Free PMC article.
The vitamin D analogue ED71 but Not 1,25(OH)2D3 targets HIF1α protein in osteoclasts.
Sato Y, Miyauchi Y, Yoshida S, Morita M, Kobayashi T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Tando T, Watanabe R, Miyamoto K, Morioka H, Matsumoto M, Toyama Y, Miyamoto T. Sato Y, et al. Among authors: hao w. PLoS One. 2014 Nov 6;9(11):e111845. doi: 10.1371/journal.pone.0111845. eCollection 2014. PLoS One. 2014. PMID: 25375896 Free PMC article.
Bcl6 promotes osteoblastogenesis through Stat1 inhibition.
Fujie A, Funayama A, Miyauchi Y, Sato Y, Kobayashi T, Kanagawa H, Katsuyama E, Hao W, Tando T, Watanabe R, Morita M, Miyamoto K, Kanaji A, Morioka H, Matsumoto M, Toyama Y, Miyamoto T. Fujie A, et al. Among authors: hao w. Biochem Biophys Res Commun. 2015 Feb 13;457(3):451-6. doi: 10.1016/j.bbrc.2015.01.012. Epub 2015 Jan 15. Biochem Biophys Res Commun. 2015. PMID: 25597995
Methotrexate inhibits osteoclastogenesis by decreasing RANKL-induced calcium influx into osteoclast progenitors.
Kanagawa H, Masuyama R, Morita M, Sato Y, Niki Y, Kobayashi T, Katsuyama E, Fujie A, Hao W, Tando T, Watanabe R, Miyamoto K, Morioka H, Matsumoto M, Toyama Y, Saya H, Miyamoto T. Kanagawa H, et al. Among authors: hao w. J Bone Miner Metab. 2016 Sep;34(5):526-31. doi: 10.1007/s00774-015-0702-2. Epub 2015 Jul 23. J Bone Miner Metab. 2016. PMID: 26202855
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.
Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T. Miyauchi Y, et al. Among authors: hao w. J Exp Med. 2010 Apr 12;207(4):751-62. doi: 10.1084/jem.20091957. Epub 2010 Apr 5. J Exp Med. 2010. PMID: 20368579 Free PMC article.
Osteoclast stimulatory transmembrane protein and dendritic cell–specific transmembrane protein cooperatively modulate cell–cell fusion to form osteoclasts and foreign body giant cells.
Miyamoto H, Suzuki T, Miyauchi Y, Iwasaki R, Kobayashi T, Sato Y, Miyamoto K, Hoshi H, Hashimoto K, Yoshida S, Hao W, Mori T, Kanagawa H, Katsuyama E, Fujie A, Morioka H, Matsumoto M, Chiba K, Takeya M, Toyama Y, Miyamoto T. Miyamoto H, et al. Among authors: hao w. J Bone Miner Res. 2012 Jun;27(6):1289-97. doi: 10.1002/jbmr.1575. J Bone Miner Res. 2012. PMID: 22337159 Free article.
Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis.
Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, Iwasaki R, Sato Y, Kobayashi T, Miyamoto H, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Kitagawa K, Nakayama KI, Kawamoto T, Sano M, Fukuda K, Ohsawa I, Ohta S, Morioka H, Matsumoto M, Chiba K, Toyama Y, Miyamoto T. Hoshi H, et al. Among authors: hao w. J Bone Miner Res. 2012 Sep;27(9):2015-23. doi: 10.1002/jbmr.1634. J Bone Miner Res. 2012. PMID: 22508505 Free article.
2,739 results