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Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M. Kim M, et al. Among authors: ro sh. Elife. 2016 Jan 26;5:e12245. doi: 10.7554/eLife.12245. Elife. 2016. PMID: 26812546 Free PMC article.
Hepatoprotective role of Sestrin2 against chronic ER stress.
Park HW, Park H, Ro SH, Jang I, Semple IA, Kim DN, Kim M, Nam M, Zhang D, Yin L, Lee JH. Park HW, et al. Among authors: ro sh. Nat Commun. 2014 Jun 20;5:4233. doi: 10.1038/ncomms5233. Nat Commun. 2014. PMID: 24947615 Free PMC article.
Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Kim JS, et al. Among authors: ro sh. Sci Rep. 2015 Mar 30;5:9502. doi: 10.1038/srep09502. Sci Rep. 2015. PMID: 25819761 Free PMC article.
Sestrins are evolutionarily conserved mediators of exercise benefits.
Kim M, Sujkowski A, Namkoong S, Gu B, Cobb T, Kim B, Kowalsky AH, Cho CS, Semple I, Ro SH, Davis C, Brooks SV, Karin M, Wessells RJ, Lee JH. Kim M, et al. Among authors: ro sh. Nat Commun. 2020 Jan 13;11(1):190. doi: 10.1038/s41467-019-13442-5. Nat Commun. 2020. PMID: 31929512 Free PMC article.
31 results